Results 51 to 60 of about 161,960 (313)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Triangulating the height of cosmic noise absorption: A method for estimating the characteristic energy of precipitating electrons [PDF]

, 2010
Energetic electrons (tens to hundreds of keV) deposit significant energy into the D layer of the ionosphere. Riometers provide a means of monitoring this electron precipitation by measuring the associated cosmic noise absorption (CNA), but individually ...
P. Wild, A. Senior, Senior, A., Kavanagh, A.J., A. J. Kavanagh, Wild, P., F. Honary, Honary, F.   +7 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Tailoring optical fibers for cell transfection [PDF]

, 2012
Optical transfection is a promising technique for the delivery of foreign genetic material into cells by transiently changing the permeability of the cell membrane.
Ma, Nan
core  

Automated analysis of spine dynamics on live CA1 pyramidal cells [PDF]

, 2015
Dendritic spines may be tiny in volume, but are of major importance for neuroscience. They are the main receivers for excitatory synaptic connections, and their constant changes in number and in shape reflect the dynamic connectivity of the brain.
Vetter, Thomas, Oertner, Thomas G., Genoud, Christel, Blumer, Clemens, Perez-Alvarez, Alberto, Vivien, Cyprien, Wiegert, J. Simon   +6 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

High resolution field imaging with atomic vapor cells [PDF]

, 2015
In this thesis, I report on the development of imaging techniques in atomic vapor cells. This is a relatively unexplored area, despite the ubiquitous use of imaging in experiments with ultracold atoms.
Horsley, Andrew
core   +1 more source

Optical and electron microscopy imaging of model circulating tumour cells

Біофізичний вісник
Background: Microscopy is a key tool in biophysical research for visualizing living cells' morphology, structure, and dynamic processes. Depending on the specific research goals, various optical and electron microscopy techniques can be applied, each ...
Марина Оленчук, Григорій Монастирський, Олена Гнатюк, А. Бойзен, Ч. Чжан, Галина Солянік, Денис Колесник, Сергій Карахім, Галина Довбешко   +8 more
doaj   +1 more source

Optical and Digital Microscopic Imaging Techniques and Applications in Pathology

Analytical Cellular Pathology, 2011
The conventional optical microscope has been the primary tool in assisting pathological examinations. The modern digital pathology combines the power of microscopy, electronic detection, and computerized analysis.
Xiaodong Chen, Bin Zheng, Hong Liu
doaj   +1 more source

Nanoparticles Produced via Laser Ablation of Porous Silicon and Silicon Nanowires for Optical Bioimaging

Sensors, 2020
Modern trends in optical bioimaging require novel nanoproducts combining high image contrast with efficient treatment capabilities. Silicon nanoparticles are a wide class of nanoobjects with tunable optical properties, which has potential as contrasting ...
Stanislav V. Zabotnov, Anastasiia V. Skobelkina, Ekaterina A. Sergeeva, Daria A. Kurakina, Aleksandr V. Khilov, Fedor V. Kashaev, Tatyana P. Kaminskaya, Denis E. Presnov, Pavel D. Agrba, Dmitrii V. Shuleiko, Pavel K. Kashkarov, Leonid A. Golovan, Mikhail Yu. Kirillin   +12 more
doaj   +1 more source