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Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly [PDF]

open access: yesPulmonary Circulation, 2020
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough   +5 more
doaj   +3 more sources

Resonant electron transmission through a finite quantum spin chain [PDF]

open access: yes, 1998
Electron transport in a finite one dimensional quantum spin chain (with ferromagnetic exchange) is studied within an $s-d$ exchange Hamiltonian. Spin transfer coefficients strongly depend on the sign of the $s-d$ exchange constant.
Boyd, Iain D.   +9 more
core   +4 more sources

Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis. [PDF]

open access: yesPLoS Computational Biology, 2012
The mitochondrial electron transport chain transforms energy satisfying cellular demand and generates reactive oxygen species (ROS) that act as metabolic signals or destructive factors.
Vitaly A Selivanov   +5 more
doaj   +6 more sources

Electron transport through a strongly correlated monoatomic chain [PDF]

open access: green, 2005
We study transport properties of a strongly correlated monoatomic chain coupled to metallic leads. Our system is described by tight binding Hubbard-like model in the limit of strong on-site electron-electron interactions in the wire.
Agraït   +38 more
core   +2 more sources

Compound C prevents Hypoxia-Inducible Factor-1α protein stabilization by regulating the cellular oxygen availability via interaction with Mitochondrial Complex I [PDF]

open access: yesBMC Research Notes, 2011
The transcription factor Hypoxia-Inducible Factor-1α is a master regulator of the cellular response to low oxygen concentration. Compound C, an inhibitor of AMP-activated kinase, has been reported to inhibit hypoxia dependent Hypoxia-Inducible Factor-1α ...
Hagen Thilo, Chua Yee Liu
doaj   +4 more sources

Yeast model uncovers dual roles of mitochondria in action of artemisinin. [PDF]

open access: yesPLoS Genetics, 2005
Artemisinins, derived from the wormwood herb Artemisia annua, are the most potent antimalarial drugs currently available. Despite extensive research, the exact mode of action of artemisinins has not been established.
Wei Li   +7 more
doaj   +8 more sources

Chemically Mediated Artificial Electron Transport Chain

open access: yesACS Central Science
Electron transport chains (ETCs) are ubiquitous in nearly all living systems. Replicating the complexity and control inherent in these multicomponent systems using ensembles of small molecules opens up promising avenues for molecular therapeutics, catalyst design, and the development of innovative energy conversion and storage systems. Here, we present
Yu-Dong Yang   +9 more
doaj   +4 more sources

Structure and mechanism of mitochondrial electron transport chain

open access: yesBiomedical Journal, 2018
Respiration is one of the most vital and basic features of living organisms. In mammals, respiration is accomplished by respiratory chain complexes located on the mitochondrial inner membrane.
Runyu Guo   +4 more
doaj   +4 more sources

Intrinsically distinct hole and electron transport in conjugated polymers controlled by intra and intermolecular interactions [PDF]

open access: yesNat Commun 10, 5226 (2019), 2019
It is still a matter of controversy whether the relative difference in hole and electron transport in solution-processed organic semiconductors is either due to intrinsic properties linked to chemical and solid-state structure or to extrinsic factors, as
Bargigia, Ilaria   +4 more
core   +2 more sources

The role of the electron transport chain in immunity [PDF]

open access: yesThe FASEB Journal, 2021
The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c) release as a signal for programmed cell death.
Maureen Yin, Luke A. J. O’Neill
openaire   +3 more sources

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