Results 41 to 50 of about 5,302,303 (289)

Compound C prevents Hypoxia-Inducible Factor-1α protein stabilization by regulating the cellular oxygen availability via interaction with Mitochondrial Complex I

BMC Research Notes, 2011
The transcription factor Hypoxia-Inducible Factor-1α is a master regulator of the cellular response to low oxygen concentration. Compound C, an inhibitor of AMP-activated kinase, has been reported to inhibit hypoxia dependent Hypoxia-Inducible Factor-1α ...
Hagen Thilo, Chua Yee Liu
doaj   +1 more source

Transcriptomic and Functional Analyses of Mitochondrial Dysfunction in Pressure Overload‐Induced Right Ventricular Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In complex congenital heart disease patients such as those with tetralogy of Fallot, the right ventricle (RV) is subject to pressure overload, leading to RV hypertrophy and eventually RV failure. The mechanisms that promote the transition from
HyunTae V. Hwang, Nefthi Sandeep, Ramesh V. Nair, Dong‐Qing Hu, Mingming Zhao, Ingrid S. Lan, Giovanni Fajardo, Scot J. Matkovich, Daniel Bernstein, Sushma Reddy   +9 more
doaj   +1 more source

Comparsion of the Effects of Succinate and NADH on Postmortem Metmyoglobin Redcutase Activity and Beef Colour Stability

Journal of Integrative Agriculture, 2014
In two experiments, the effects of succinate and NADH (reduced nicotinamide adenine dinucleotide) on metmyoglobin reductase activity and electron transport chain-linked metmyoglobin reduction were investigated and compared. In experiment 1, metmyoglobin (
Xiao-guang GAO, Zhen-yu WANG, Meng-tian TANG, Chang-wei MA, Rui-tong DAI   +4 more
doaj   +1 more source

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

PLoS ONE, 2021
BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova, Erwin E W Jansen, Jessie Cameron, Rob Barto, Thomas Hurd, Lauren MacNeil, Gajja S Salomons, Saadet Mercimek-Andrews   +7 more
doaj   +1 more source

24-epibrassinolide improved chilled tomato photosynthetic performance by stabilizing electron transport chain and function of photosystem II

Biologia Plantarum, 2022
To explore the protective mechanisms of brassinosteroids in the chill-induced photoinhibition in tomato (Solanum lycopersicum), we studied the effect of foliar sprayed 24-epibrassinolide (EBR, 0.1µM) on the gas exchange, chlorophyll fluorescence ...
W.-H. HU, X.-H. HU, C. LIU, B.-Q. WANG, X.-H. YAN   +4 more
doaj   +1 more source

Electron transport chain inhibition increases cellular dependence on purine transport and salvage. [PDF]

Cell Metab
Wu Z, Bezwada D, Cai F, Harris RC, Ko B, Sondhi V, Pan C, Vu HS, Nguyen PT, Faubert B, Cai L, Chen H, Martin-Sandoval M, Do D, Gu W, Zhang Y, Zhang Y, Brooks B, Kelekar S, Zacharias LG, Oaxaca KC, Patricio JS, Mathews TP, Garcia-Bermudez J, Ni M, DeBerardinis RJ.   +25 more
europepmc   +2 more sources

Electronic and Transport Properties of Artificial Gold Chains [PDF]

Physical Review Letters, 2004
We study the electronic and transport properties of artificial Au atomic chains on a NiAl(110) surface template using state-of-the-art first principles calculations. Au chains display remarkable one-dimensional electronic properties that can be tuned by the selective adsorption of small molecules: a single CO group is shown to modulate the electronic ...
Arrigo Calzolari, Carlo Cavazzoni, Marco Buongiorno Nardelli   +2 more
openaire   +5 more sources

The Electron Transport Chain

The American Biology Teacher, 2014
This activity provides students an interactive demonstration of the electron transport chain and chemiosmosis during aerobic respiration. Students use simple, everyday objects as hydrogen ions and electrons and play the roles of the various proteins embedded in the inner mitochondrial membrane to show how this specific process in cellular respiration ...
Chris Romero, James Choun
openaire   +1 more source

Electron transport chain paired and individual complexes.

, 2021
Electron transport chain paired and individual complexes in muscle biopsy specimen are depicted, which shows decreased paired and individual complex activities in Patient 1 compared to controls.
Anastasia Minenkova (11408438), Rob Barto (11408447), Saadet Mercimek-Andrews (4526929), Thomas Hurd (11408450), Erwin E. W. Jansen (11408441), Jessie Cameron (11408444), Gajja S. Salomons (4526917), Lauren MacNeil (397730)   +7 more
core   +1 more source

A Biophysical Systems Approach to Identifying the Pathways of Acute and Chronic Doxorubicin Mitochondrial Cardiotoxicity. [PDF]

PLoS Computational Biology, 2016
The clinical use of the anthracycline doxorubicin is limited by its cardiotoxicity which is associated with mitochondrial dysfunction. Redox cycling, mitochondrial DNA damage and electron transport chain inhibition have been identified as potential ...
Bernardo L de Oliveira, Steven Niederer
doaj   +1 more source