Results 11 to 20 of about 191,588 (193)

Structure and mechanism of mitochondrial electron transport chain

Biomedical Journal, 2018
Respiration is one of the most vital and basic features of living organisms. In mammals, respiration is accomplished by respiratory chain complexes located on the mitochondrial inner membrane.
Runyu Guo, Jinke Gu, Shuai Zong, Meng Wu, Maojun Yang   +4 more
doaj   +4 more sources

Chemically Mediated Artificial Electron Transport Chain

ACS Central Science
Electron transport chains (ETCs) are ubiquitous in nearly all living systems. Replicating the complexity and control inherent in these multicomponent systems using ensembles of small molecules opens up promising avenues for molecular therapeutics, catalyst design, and the development of innovative energy conversion and storage systems. Here, we present
Yu-Dong Yang, Qian Zhang, Lhoussain Khrouz, Calvin V. Chau, Jian Yang, Yuying Wang, Christophe Bucher, Graeme Henkelman, Han-Yuan Gong, Jonathan L. Sessler   +9 more
doaj   +4 more sources

The role of the electron transport chain in immunity [PDF]

The FASEB Journal, 2021
The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c) release as a signal for programmed cell death.
Maureen Yin, Luke A. J. O’Neill
openaire   +3 more sources

Regulation and functional role of the electron transport chain supercomplexes [PDF]

Biochemical Society Transactions, 2021
Mitochondria are one of the most exhaustively investigated organelles in the cell and most attention has been paid to the components of the mitochondrial electron transport chain (ETC) in the last 100 years. The ETC collects electrons from NADH or FADH2 and transfers them through a series of electron carriers within multiprotein respiratory complexes ...
José Luis Cabrera-Alarcón, Sara Cogliati, Sara Cogliati, José Antonio Enríquez   +3 more
openaire   +6 more sources

APOE expression and secretion are modulated by mitochondrial dysfunction

eLife, 2023
Mitochondria influence cellular function through both cell-autonomous and non-cell autonomous mechanisms, such as production of paracrine and endocrine factors.
Meghan E Wynne, Oluwaseun Ogunbona, Alicia R Lane, Avanti Gokhale, Stephanie A Zlatic, Chongchong Xu, Zhexing Wen, Duc M Duong, Sruti Rayaprolu, Anna Ivanova, Eric A Ortlund, Eric B Dammer, Nicholas T Seyfried, Blaine R Roberts, Amanda Crocker, Vinit Shanbhag, Michael Petris, Nanami Senoo, Selvaraju Kandasamy, Steven Michael Claypool, Antoni Barrientos, Aliza Wingo, Thomas S Wingo, Srikant Rangaraju, Allan I Levey, Erica Werner, Victor Faundez   +26 more
doaj   +1 more source

Mitochondrial Complex Abundance, Mitophagy Proteins, and Physical Performance in People With and Without Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Mitochondrial abnormalities exist in gastrocnemius muscle of people with peripheral artery disease (PAD). Whether abnormalities in mitochondrial biogenesis and autophagy are associated with greater ischemia or walking impairment in PAD is ...
Anna Picca, Stephanie E. Wohlgemuth, Mary M. McDermott, Sunil K. Saini, Sudarshan Dayanidhi, Dongxue Zhang, Shujun Xu, Kate Kosmac, Lu Tian, Luigi Ferrucci, Robert L. Sufit, Emanuele Marzetti, Christiaan Leeuwenburgh   +12 more
doaj   +1 more source

Diversity of electron transport chains in anaerobic protists

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2021
Eukaryotic microbes (protists) that occupy low-oxygen environments often have drastically different mitochondrial metabolism compared to their aerobic relatives. A common theme among many anaerobic protists is the serial loss of components of the electron transport chain (ETC). Here, we discuss the diversity of the ETC across the tree of eukaryotes and
Gawryluk, Ryan M. R., Stairs, Courtney W.   +1 more
openaire   +4 more sources

Transcriptomic and Functional Analyses of Mitochondrial Dysfunction in Pressure Overload‐Induced Right Ventricular Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In complex congenital heart disease patients such as those with tetralogy of Fallot, the right ventricle (RV) is subject to pressure overload, leading to RV hypertrophy and eventually RV failure. The mechanisms that promote the transition from
HyunTae V. Hwang, Nefthi Sandeep, Ramesh V. Nair, Dong‐Qing Hu, Mingming Zhao, Ingrid S. Lan, Giovanni Fajardo, Scot J. Matkovich, Daniel Bernstein, Sushma Reddy   +9 more
doaj   +1 more source

Coordinating Electron Transport Chains to an Electron Donor

Organic Letters, 2015
Two electron transport chains (2 and 3) featuring two fullerenes with different electron acceptor strengths have been synthesized, characterized, and coordinated to a light harvesting/electron donating zinc porphyrin. Electrochemical assays corroborate the redox gradients along the designed electron transport chains, and complementary absorption and ...
Carmen Villegas, Dirk M. Guldi, Maximilian Wolf, Nazario Martín, Nazario Martín, Juan Luis Delgado, Juan Luis Delgado, Damien Joly   +7 more
openaire   +4 more sources

The Electron Transport Chain

The American Biology Teacher, 2014
This activity provides students an interactive demonstration of the electron transport chain and chemiosmosis during aerobic respiration. Students use simple, everyday objects as hydrogen ions and electrons and play the roles of the various proteins embedded in the inner mitochondrial membrane to show how this specific process in cellular respiration ...
Chris Romero, James Choun
openaire   +2 more sources