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Analyzing electron transport chain supercomplexes

Methods in Cell Biology, 2020
This review focuses on three independent and complementary approaches to obtain information on the combined function of respiratory complexes when present in different structural situations, either as individual complexes or when superassembled with other complexes.
Rebeca, Acín-Pérez   +2 more
openaire   +3 more sources

Regulation of Mitochondrial Electron Transport Chain Assembly

Journal of Molecular Biology, 2018
Mitochondrial function depends on the correct synthesis, transport, and assembly of proteins and cofactors of the electron transport chain. The initial idea that the respiratory chain protein complexes (RCCs) were independent structures in the inner mitochondrial membrane evolved after the identification of higher quaternary structures called ...
Cogliati, Sara   +4 more
openaire   +4 more sources

"Electron Transport Chain Interference" Strategy of Amplified Mild-Photothermal Therapy and Defect-Engineered Multi-Enzymatic Activities for Synergistic Tumor-Personalized Suppression.

Journal of the American Chemical Society, 2023
Arming activatable mild-photothermal therapy (PTT) with the property of relieving tumor thermotolerance holds great promise for overcoming traditional mild PTT limitations such as thermoresistance, insufficient therapeutic effect, and off-target heating.
Shuming Dong   +9 more
semanticscholar   +1 more source

Electron transport chains

2023
This chapter considers electron transport chains. Two of the most fundamental metabolic processes, aerobic respiration and photosynthesis, which play such a critical role in maintaining life on Earth, require a succession of electron transfers. In both processes the electron transfers take place in membrane-localized electron transport chains that ...
Peter Atkins   +3 more
openaire   +1 more source

Disorders of the electron transport chain

Journal of Inherited Metabolic Disease, 1996
SummaryDefects in a pathway as complex as the electron transport chain cause a variety of clinical abnormalities, which vary from fatal lactic acidosis in infancy to mild muscle disease in adults. The primary defect may reside in the nucleus or the mitochondrial genome.
P L, Adams, D M, Turnbull
openaire   +2 more sources

Characterizing the Electron Transport Chain: Structural Approach

2022
The mitochondrial respiratory chain which carries out the oxidative phosphorylation (OXPHOS) consists of five multi-subunit protein complexes. Emerging evidences suggest that the supercomplexes which further consist of multiple respiratory complexes play important role in regulating OXPHOS function.
Ting, Liang   +5 more
openaire   +2 more sources

Pseudogenes and The Electron Transport Chain

2007
With the advent of easy access to the human genome sequence, molecular biology techniques to target respirome-specific genes have begun to be exploited in the study of human disorders and in particular human cancers. In some recent publications it would appear that some investigators have inappropriately targeted pseudogenes rather than functional ...
Oey, H. M., Maguire D. J., McCabe, M.
openaire   +3 more sources

Electron Transport Chain Defects in Heart Failure

Heart Failure Reviews, 2002
In recent years, the possibility that disorders of cardiac metabolism play a role in the mechanisms that lead to ventricular dilatation and dysfunction in heart failure has attracted much attention. Electron transport chain is constituted by a series of multimeric protein complexes, located in the inner mitochondrial membranes, whose genes are ...
Jordi, Casademont, Oscar, Miró
openaire   +2 more sources

Regulation of the photosynthetic electron transport chain

Planta, 1999
The regulation of electron transport between photosystems II and I was investigated in the plant Silene dioica L. by means of measurement of the kinetics of reduction of P(700) following a light-to-dark transition. It was found that, in this species, the rate constant for P(700) reduction is sensitive to light intensity and to the availability of CO(2).
Ott, Thomas   +3 more
openaire   +3 more sources

Biological Redox Mediation in Electron Transport Chain of Bacteria for Oxygen Reduction Reaction Catalysts in Lithium–Oxygen Batteries

Advanced Functional Materials, 2018
Governing the fundamental reaction in lithium–oxygen batteries is vital to realizing their potentially high energy density. Here, novel oxygen reduction reaction (ORR) catalysts capable of mediating the lithium and oxygen reaction within a solution ...
Youngmin Ko   +9 more
semanticscholar   +1 more source

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