Results 21 to 30 of about 554,215 (338)

Fumarate is a terminal electron acceptor in the mammalian electron transport chain

Science, 2021
Description Reversing the chain The mitochondrial electron transport chain is a major part of cellular metabolism and plays key roles in both cellular respiration and the synthesis of critical metabolites.
J. Spinelli, Paul C. Rosen, Hans-Georg Sprenger, Anna M. Puszynska, Jessica L. Mann, Julian M. Roessler, Andrew L. Cangelosi, Antonia Henne, K. J. Condon, Tong Zhang, Tenzin Kunchok, C. Lewis, N. Chandel, D. Sabatini   +13 more
semanticscholar   +1 more source

Mechanisms and mathematical modelling of ROS production by the mitochondrial electron transport chain.

American Journal of Physiology - Cell Physiology, 2022
Reactive oxygen species (ROS) are recognised both as damaging molecules and intracellular signalling entities. In addition to its role in ATP generation, the mitochondrial electron transport chain (ETC) constitutes a relevant source of mitochondrial ROS,
Sandeep Chenna, W. Koopman, J. Prehn, N. Connolly   +3 more
semanticscholar   +1 more source

In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors

Science Advances, 2022
In mice and humans with cancer, intravenous 13C-glucose infusion results in 13C labeling of tumor tricarboxylic acid (TCA) cycle intermediates, indicating that pyruvate oxidation in the TCA cycle occurs in tumors.
Panayotis Pachnis, Zheng Wu, B. Faubert, Alpaslan Tasdogan, Wen Gu, Spencer D Shelton, Ashley Solmonson, A. Rao, Akash K. Kaushik, Thomas J Rogers, Jessalyn M. Ubellacker, Collette A. LaVigne, Chendong Yang, Bookyung Ko, V. Ramesh, J. Sudderth, L. Zacharias, Misty S. Martin-Sandoval, Duyen Do, Thomas P Mathews, Zhiyu Zhao, Prashant Mishra, S. Morrison, R. Deberardinis   +23 more
semanticscholar   +1 more source

The role of the electron transport chain in immunity

The FASEB Journal, 2021
The electron transport chain (ETC) couples oxidative phosphorylation (OXPHOS) with ATP synthase to drive the generation of ATP. In immune cells, research surrounding the ETC has drifted away from bioenergetics since the discovery of cytochrome c (Cyt c ...
Maureen Yin, L. O’Neill
semanticscholar   +1 more source

Regulation and functional role of the electron transport chain supercomplexes

Biochemical Society Transactions, 2021
Mitochondria are one of the most exhaustively investigated organelles in the cell and most attention has been paid to the components of the mitochondrial electron transport chain (ETC) in the last 100 years.
S. Cogliati, J. Cabrera-Alarcon, J. Enríquez   +2 more
semanticscholar   +1 more source

ETMB-RBF: discrimination of metal-binding sites in electron transporters based on RBF networks with PSSM profiles and significant amino acid pairs. [PDF]

PLoS ONE, 2013
BACKGROUND: Cellular respiration is the process by which cells obtain energy from glucose and is a very important biological process in living cell. As cells do cellular respiration, they need a pathway to store and transport electrons, the electron ...
Yu-Yen Ou, Shu-An Chen, Sheng-Cheng Wu
doaj   +1 more source

Rel-dependent decrease in the expression of ribosomal protein genes by inhibition of the respiratory electron transport chain in Mycobacterium smegmatis. [PDF]

Front Microbiol
Kim NK, Baek JE, Lee YJ, Oh Y, Oh JI.
europepmc   +3 more sources

Electron Transport Chain Complex II Regulates Steroid Metabolism

iScience, 2020
Summary: The first steroidogenic enzyme, cytochrome P450-side-chain-cleavage (SCC), requires electron transport chain (ETC) complexes III and IV to initiate steroid metabolic processes for mammalian survival.
Himangshu S. Bose, Brendan Marshall, Dilip K. Debnath, Elizabeth W. Perry, Randy M. Whittal   +4 more
doaj   +1 more source

Electron Transport Chain (ETC)

Sabuj Afridi
openalex   +2 more sources

Deletion of Von Willebrand A Domain Containing Protein (VWA8) raises activity of mitochondrial electron transport chain complexes in hepatocytes

Biochemistry and Biophysics Reports, 2021
VWA8 (Von Willebrand A Domain Containing Protein 8) is a AAA+ ATPase that is localized to the mitochondrial matrix and is widely expressed in highly energetic tissues.
Moulun Luo, Wuqiong Ma, Rocio Zapata-Bustos, Wayne T. Willis, Lawrence J. Mandarino   +4 more
doaj   +1 more source