Results 21 to 30 of about 500,172 (279)

Is impaired energy production a novel insight into the pathogenesis of pyridoxine-dependent epilepsy due to biallelic variants in ALDH7A1?

open access: yesPLoS ONE, 2021
BackgroundPyridoxine-dependent epilepsy (PDE) is due to biallelic variants in ALDH7A1 (PDE-ALDH7A1). ALDH7A1 encodes α-aminoadipic semialdehyde dehydrogenase in lysine catabolism.
Anastasia Minenkova   +7 more
doaj   +1 more source

Cluster-based density-functional approach to quantum transport through molecular and atomic contacts [PDF]

open access: yes, 2008
We present a cluster-based density-functional approach to model charge transport through molecular and atomic contacts. The electronic structure of the contacts is determined in the framework of density functional theory, and the parameters needed to ...
Akkerman H B   +26 more
core   +3 more sources

A Biophysical Systems Approach to Identifying the Pathways of Acute and Chronic Doxorubicin Mitochondrial Cardiotoxicity. [PDF]

open access: yesPLoS Computational Biology, 2016
The clinical use of the anthracycline doxorubicin is limited by its cardiotoxicity which is associated with mitochondrial dysfunction. Redox cycling, mitochondrial DNA damage and electron transport chain inhibition have been identified as potential ...
Bernardo L de Oliveira, Steven Niederer
doaj   +1 more source

Crossover from time-correlated single-electron tunneling to that of Cooper pairs

open access: yes, 2007
We have studied charge transport in a one-dimensional chain of small Josephson junctions using a single-electron transistor. We observe a crossover from time-correlated tunneling of single electrons to that of Cooper pairs as a function of both magnetic ...
D. V. Averin   +8 more
core   +1 more source

Inelastic electron transport in polymer nanofibers

open access: yes, 2008
In this paper we present theoretical analysis of the electron transport in conducting polymers. We concentrate on the study of the effects of temperature on characteristics of the transport. We treat a conducting polymers in a metal state as a network of
Mott N. F., Natalya A. Zimbovskaya
core   +1 more source

Plastid redox state and sugars: Interactive regulators of nuclear-encoded photosynthetic gene expression [PDF]

open access: yes, 2001
Feedback regulation of photosynthesis by carbon metabolites has long been recognized, but the underlying cellular mechanisms that control this process remain unclear.
Dominy, P J   +3 more
core   +2 more sources

Genes Involved in Maintaining Mitochondrial Membrane Potential Upon Electron Transport Chain Disruption

open access: yesFrontiers in Cell and Developmental Biology, 2022
Mitochondria are biosynthetic, bioenergetic, and signaling organelles with a critical role in cellular physiology. Dysfunctional mitochondria are associated with aging and underlie the cause of a wide range of diseases, from neurodegeneration to cancer ...
Karthik Vasan   +7 more
doaj   +1 more source

Rashba effect induced localization in quantum networks [PDF]

open access: yes, 2004
We study a quantum network extending in one-dimension (chain of square loops connected at one vertex) made up of quantum wires with Rashba spin-orbit coupling. We show that the Rashba effect may give rise to an electron localization phenomenon similar to
B. Altshuler   +9 more
core   +2 more sources

A Feed-Forward Circuit of Endogenous PGC-1α and Estrogen Related Receptor α Regulates the Neuronal Electron Transport Chain

open access: yesParkinson's Disease, 2016
Peroxisome proliferator-activated receptor  γ coactivator 1α (PGC-1α) is a central regulator of cellular and mitochondrial metabolism. Cellular bioenergetics are critically important in “energy-guzzling” neurons, but the components and wiring of the ...
Rachit Bakshi   +3 more
doaj   +1 more source

Coulomb Gap in Graphene Nanoribbons

open access: yes, 2011
We investigate the density and temperature-dependent conductance of graphene nanoribbons with varying aspect ratio. Transport is dominated by a chain of quantum dots forming spontaneously due to disorder. Depending on ribbon length, electron density, and
Dröscher, S.   +4 more
core   +1 more source

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