Results 31 to 40 of about 554,215 (338)

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

International Journal of Molecular Medicine, 2019
The mammalian mitochondrial electron transport chain (ETC) includes complexes I-IV, as well as the electron transporters ubiquinone and cytochrome c. There are two electron transport pathways in the ETC: Complex I/III/IV, with NADH as the substrate and ...
Ruzhou Zhao, Shuai Jiang, Lin Zhang, Zhi-Bin Yu   +3 more
semanticscholar   +1 more source

Yeast model uncovers dual roles of mitochondria in action of artemisinin. [PDF]

PLoS Genetics, 2005
Artemisinins, derived from the wormwood herb Artemisia annua, are the most potent antimalarial drugs currently available. Despite extensive research, the exact mode of action of artemisinins has not been established.
Wei Li, Weike Mo, Dan Shen, Libo Sun, Juan Wang, Shan Lu, Jane M Gitschier, Bing Zhou   +7 more
doaj   +2 more sources

APOE expression and secretion are modulated by mitochondrial dysfunction

eLife, 2023
Mitochondria influence cellular function through both cell-autonomous and non-cell autonomous mechanisms, such as production of paracrine and endocrine factors.
Meghan E Wynne, Oluwaseun Ogunbona, Alicia R Lane, Avanti Gokhale, Stephanie A Zlatic, Chongchong Xu, Zhexing Wen, Duc M Duong, Sruti Rayaprolu, Anna Ivanova, Eric A Ortlund, Eric B Dammer, Nicholas T Seyfried, Blaine R Roberts, Amanda Crocker, Vinit Shanbhag, Michael Petris, Nanami Senoo, Selvaraju Kandasamy, Steven Michael Claypool, Antoni Barrientos, Aliza Wingo, Thomas S Wingo, Srikant Rangaraju, Allan I Levey, Erica Werner, Victor Faundez   +26 more
doaj   +1 more source

Polymer-Modified Single-Walled Carbon Nanotubes Affect Photosystem II Photochemistry, Intersystem Electron Transport Carriers and Photosystem I End Acceptors in Pea Plants

Molecules, 2021
Single-walled carbon nanotubes (SWCNT) have recently been attracting the attention of plant biologists as a prospective tool for modulation of photosynthesis in higher plants.
Nia Petrova, Momchil Paunov, Petar Petrov, Violeta Velikova, Vasilij Goltsev, Sashka Krumova   +5 more
doaj   +1 more source

Vitamin K2 in Electron Transport System: Are Enzymes Involved in Vitamin K2 Biosynthesis Promising Drug Targets?

Molecules, 2010
Aerobic and anaerobic respiratory systemsallow cells to transport the electrons to terminal electron acceptors. The quinone (ubiquinone or menaquinone) pool is central to the electron transport chain. In the majority of Gram-positive bacteria, vitamin K2
Eeshwaraiah Begari, Michio Kurosu
doaj   +1 more source

Endurance exercise training in pulmonary hypertension increases skeletal muscle electron transport chain supercomplex assembly

Pulmonary Circulation, 2020
Pulmonary hypertension is associated with pronounced exercise intolerance (decreased V ċ O 2 max) that can significantly impact quality of life. The cause of exercise intolerance in pulmonary hypertension remains unclear. Mitochondrial supercomplexes are
Danielle J. McCullough, Nouaying Kue, Thomas Mancini, Alexander Vang, Richard T. Clements, Gaurav Choudhary   +5 more
doaj   +1 more source

The Significance of Chloroplast NAD(P)H Dehydrogenase Complex and Its Dependent Cyclic Electron Transport in Photosynthesis

Frontiers in Plant Science, 2021
Chloroplast NAD(P)H dehydrogenase (NDH) complex, a multiple-subunit complex in the thylakoid membranes mediating cyclic electron transport, is one of the most important alternative electron transport pathways.
Mingzhu Ma, Yifei Liu, Yifei Liu, Yifei Liu, Yifei Liu, Chunming Bai, Chunming Bai, Jean Wan Hong Yong, Jean Wan Hong Yong   +8 more
doaj   +1 more source

Mitochondrial Complex Abundance, Mitophagy Proteins, and Physical Performance in People With and Without Peripheral Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Mitochondrial abnormalities exist in gastrocnemius muscle of people with peripheral artery disease (PAD). Whether abnormalities in mitochondrial biogenesis and autophagy are associated with greater ischemia or walking impairment in PAD is ...
Anna Picca, Stephanie E. Wohlgemuth, Mary M. McDermott, Sunil K. Saini, Sudarshan Dayanidhi, Dongxue Zhang, Shujun Xu, Kate Kosmac, Lu Tian, Luigi Ferrucci, Robert L. Sufit, Emanuele Marzetti, Christiaan Leeuwenburgh   +12 more
doaj   +1 more source

Transcriptomic and Functional Analyses of Mitochondrial Dysfunction in Pressure Overload‐Induced Right Ventricular Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background In complex congenital heart disease patients such as those with tetralogy of Fallot, the right ventricle (RV) is subject to pressure overload, leading to RV hypertrophy and eventually RV failure. The mechanisms that promote the transition from
HyunTae V. Hwang, Nefthi Sandeep, Ramesh V. Nair, Dong‐Qing Hu, Mingming Zhao, Ingrid S. Lan, Giovanni Fajardo, Scot J. Matkovich, Daniel Bernstein, Sushma Reddy   +9 more
doaj   +1 more source

Correction: A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites. [PDF]

PLoS Pathog
Hayward JA, Makota FV, Cihalova D, Leonard RA, Rajendran E, Zwahlen SM, Shuttleworth L, Wiedemann U, Spry C, Saliba KJ, Maier AG, Dooren GGV.   +11 more
europepmc   +3 more sources