Results 161 to 170 of about 441,339 (185)

Glial cells are involved in Day–Night protein dysregulation in the hippocampus of a mouse model of Alzheimer’s disease

Badina AM, Tahiri H, Ouarour A, Ceyzériat K, Millet P, Tournier BB, Chakir I.   +6 more
europepmc   +1 more source

The genetic origin of fetal growth restriction and mitochondrial complex I dysregulation

Fisher JJ, Wang CA, Botha VB, Acharya S, Murray HC, Schjenken JE, Pennell CE, Smith R.   +7 more
europepmc   +1 more source

Understanding molecular biology of codon usage in mitochondrial complex IV genes of electron transport system: Relevance to mitochondrial diseases

Journal of Cellular Physiology, 2018
AbstractThe mitochondrial cytochrome oxidase (CO) genes are involved in complex IV of the electron transport system, and dysfunction of CO genes leads to several diseases. However, no work has been reported on the codon usage pattern of these genes. We used bioinformatic methods to analyze the compositional properties and the codon usage pattern of the
Arif Uddin, Tarikul Huda Mazumder, Supriyo Chakraborty   +2 more
semanticscholar   +5 more sources

Abstract 57: Erythropoietin Selectively Preserves Electron Transport Complex IV Activity During Resuscitation from Cardiac Arrest

Circulation, 2011
Introduction: We have previously documented in a rat model of VF and closed-chest resuscitation that administration of erythropoietin (EPO) preserves left ventricular distensibility - yielding hemodynamically more effective CPR - and attenuates post-resuscitation myocardial dysfunction ...
Jeejabai Radhakrishnan, Hawnyeu M Moy, Raúl J. Gazmuri   +2 more
semanticscholar   +3 more sources

l‐DOPA Inhibits Complex IV of the Electron Transport Chain in Catecholamine‐Rich Human Neuroblastoma NB69 Cells

Journal of Neurochemistry, 1995
Abstract: l‐3,4‐Dihydroxyphenylalanine (l‐DOPA) is toxic for human neuroblastoma cells NB69 and its toxicity is related to several mechanisms including quinone formation and enhanced production of free radicals related to the metabolism of dopamine via monoamine oxidase type B.
Beatriz Pardo, María A. Mena, Justo Garcı́a de Yébenes   +2 more
semanticscholar   +5 more sources

Bezafibrate induced increase in mitochondrial electron transport chain complex IV activity in human astrocytoma cells: Implications for mitochondrial cytopathies and neurodegenerative diseases

BioFactors, 2010
AbstractMitochondrial encephalomyopathies resulting from electron transport chain (ETC) dysfunction can present with a wide spectrum of clinical manifestations having significant neuropathology and a progressive nature. Despite advances in diagnosis of ETC disorders, treatment still remains inadequate.
Nicola Ioannou, Iain P. Hargreaves, G Allen, Kate Duberley, John M. Land, Simon Heales   +5 more
semanticscholar   +4 more sources

Loss of hepatic cytochrome aa3 during chronic valproate treatment: dissociation of proton pumping and electron transport in Complex IV

Biochemical Society Transactions, 1991
Sylvie Ponchaut, Jean‐Pierre Draye, François Van Hoof, Keith Veitch   +3 more
semanticscholar   +5 more sources

Involvement of water in electron transport in complexes III and IV of the mitochondrial electron transport chain

Biochemical and Biophysical Research Communications, 1966
In this communication we present some preliminary findings on the “cross-over points” which we observed when isolated electron transport complexes III and IV from beef heart mitochondria were studied in 90% glycerol. Three considerations led us to study electron transport in a medium of low water activity: 1) Such studies might allow the resolution of ...
H. Baum, John S. Rieske
openalex   +4 more sources

Diffuse Cortical Gliosis Is Associated with Decreased Mitochondrial Electron Transport Chain Complex IV Activity in Epileptogenic Brain Resected from Children with Intractable Epilepsy (PD3.003)

Neurology, 2012
Michael V. Miles, Lili Miles, Francesco T. Mangano, Paul S. Horn, Hansel M. Greiner, James L. Leach, K. H. Lee, Ton J. deGrauw, Charles L. Hoppel   +8 more
openalex   +2 more sources

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Switching ubiquitous and muscle‐specific isoforms of mitochondrial respiratory complex IV in skeletal muscle fine‐tunes complex IV activity

The FASEB Journal, 2023
Respiratory complex IV (CIV, cytochrome c oxidase) is the terminal enzyme of the mitochondrial electron transport chain. Some CIV subunits have two or more isoforms, which are ubiquitously expressed or are expressed in specific tissues like the lung ...
Xianglai Ye, Yaojun Xie, Yu Shi, Bo Wang, Xinyu Han, Xiaoping Zhou, Kexin Pan, Mao-feng Wang, Hezhi Fang   +8 more
semanticscholar   +1 more source