Results 51 to 60 of about 7,672,012 (305)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

New electronic habit reminder for the management of thumb-sucking habit

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2016
Methods for intervention of nonnutritive sucking habits include counseling, positive reinforcement, calendar with rewards, adhesive bandage, bitter nail polish, long sleeves, and appliance therapy.
Srinath Krishnappa, M S Rani, Sandeep Aariz   +2 more
doaj   +1 more source

UTILIZATION OF ARDUINO-BASED BLUETOOTH CONNECTION FOR ELECTRONIC EQUIPMENT CONTROL WITH VOICE COMMANDS

Jurnal Riset Informatika, 2021
Electronic equipment is a daily necessity in human life, but not infrequently we use electronic equipment excessively or ineffectively and the main problem is the factor of forgetting and being lazy to turn off electronic equipment.
Hafdiarsya Saiyar
doaj   +1 more source

Long-lived oscillatory incoherent electron dynamics in molecules: trans-polyacetylene oligomers [PDF]

, 2013
We identify an intriguing feature of the electron-vibrational dynamics of molecular systems via a computational examination of \emph{trans}-polyacetylene oligomers.
Brumer, Paul, Franco, Ignacio, Rubio, Angel   +2 more
core   +3 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Association Between Time Spent on Electronic Devices and Body Mass Index in Young Adults

Journal of Multidisciplinary Healthcare, 2022
Nazish Rafique,1 Gaeda Khaled I Alkaltham,2 Latifah Abdullah A Almulhim,3 Lubna Ibrahim Al-Asoom,1 Ahmed A AlSunni,1 Rabia Latif,1 Mona Hmoud AlSheikh,1 Talay Yar,1 Kholoud S Al Ghamdi,1 Aseel Salah Alabdulhadi,4 Farhat Nadeem Saudagar,1 Samina Wasi5 ...
Rafique N, Alkaltham GKI, Almulhim LAA, Al-Asoom LI, AlSunni AA, Latif R, AlSheikh MH, Yar T, Al Ghamdi KS, Alabdulhadi AS, Saudagar FN, Wasi S   +11 more
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Electronic spin working mechanically [PDF]

, 2014
A single-electron tunneling (SET) device with a nanoscale central island that can move with respect to the bulk source- and drain electrodes allows for a nanoelectromechanical (NEM) coupling between the electrical current through the device and ...
A. V. Parafilo, Abrikosov A. A., Anderson P. W., Fransson J., Galperin M., Garanin D. A., Glazman L. I., Glazman L. I., Gorelik L. Y., I. V. Krive, K. Kikoin, Kulik I. O., Kulik I. O., L. Y. Gorelik, M. Jonson, M. N. Kiselev, Pustilnik M., R. I. Shekhter, S. I. Kulinich, Shekhter R. I., Shekhter R. I., Shekhter R. I., Shekhter R. I., Sun J. Z., Tokura Y.   +24 more
core   +2 more sources

High Energy Electron-Electron Scattering [PDF]

Physical Review, 1952
Eradicated electron sensitive nuclear emulsions were exposed to 200-Mev electrons at the Berkeley synchrotron. In scanning the electron tracks 427 events were observed in which the scattered electron of lower energy, or knock-on electron, had an energy greater than 30 kev.
Barkas, Walter H., Deutsch, Robert W., Gilbert, F.C., Violet, Charles E.   +3 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source