Transforming Grain‐Boundary Brittle Precipitates to Ductility Pathways in Complex Concentrated Alloy
By engineering graded BCC/L12 interfaces, brittle precipitates in a complex concentrated alloy enable sequential deformation, realizing gigapascal strength with >20% elongation to solve the strength‐ductility trade‐off. ABSTRACT Conventional wisdom holds that hard grain‐boundary (GB) precipitates embrittle structural alloys by acting as crack ...
Zhixin Li +14 more
wiley +1 more source
Digital inclusion - invisible work and grey zones for nurses, acting as frontline workers. [PDF]
Moe CE, Skaarup S.
europepmc +1 more source
Generating Dynamic Structures Through Physics‐Based Sampling of Predicted Inter‐Residue Geometries
While static structure prediction has been revolutionized, modeling protein dynamics remains elusive. trRosettaX2‐Dynamics is presented to address this challenge. This framework leverages a Transformer‐based network to predict inter‐residue geometric constraints, guiding conformation generation via physics‐based iterative sampling. The resulting method
Chenxiao Xiang +3 more
wiley +1 more source
Characteristics and dynamic evolution of inter-industry volatility spillovers in China's stock market. [PDF]
Xie F, Wei H.
europepmc +1 more source
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
Viability of Dental Pulp Derived Stem Cells After Long-Term Cryopreservation. [PDF]
Malik MA +5 more
europepmc +1 more source
Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley +1 more source
Psychometric evaluation and clustering of the Chinese Community Integration Questionnaire-Revised (CIQ-R) among older adults: a cross-sectional study. [PDF]
Wang Y +7 more
europepmc +1 more source
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang +9 more
wiley +1 more source
Use of Digital Technology Among Older Adults in Poland With and Those Without Near Visual Impairment: Cross-Sectional Study. [PDF]
Lange A +4 more
europepmc +1 more source

