ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Integrated public-access computer systems: the heart of the electronic university [PDF]
It has often been said that the library is the heart of the university. As the central repository of recorded knowledge on campus, the library is an essential resource for scholarly activity, and one measure of the greatness of a university is its ...
Bailey, Jr., Charles W.
core +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Are Computers Good for Children? The Effects of Home Computers on Educational Outcomes [PDF]
Although computers are universal in the classroom, nearly twenty million children in the United States do not have computers in their homes. Surprisingly, only a few previous studies explore the role of home computers in the educational process.
Daniel O. Beltran +2 more
core
Hybrid DRL-Enhanced ACO-WWO for Efficient Resource Allocation and Load-Balancing in Cloud Computing
The growing complexity of cloud computing necessitates astute workload allocation and adaptive resource management to enhance performance while minimizing expenses and energy consumption.
Umesh Kumar Lilhore +8 more
doaj +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Accountants-electronic data processing and management science /operational research specialists relationships: an empirical investigation with special reference to British industry. [PDF]
This research project was inspired by the researcher's perception of 'the discrepancy between earlier expectations and the present state of the art with regard to the scope, quality, and features of the collaborative efforts of accountants on the one ...
Noor, Anas El-Sayed El-Sayed
core +2 more sources
In this paper, the author introduces the Neural-ODE Hybrid Block Method, which serves as a direct solution for solving higher-order ODEs. Many single and multi-step methods employed in numerical approximations lose their stability when applied in the ...
V. Murugesh +7 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source

