Results 71 to 80 of about 669,329 (344)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Categorizer Agent for Electronic Computer Science Academic Papers [PDF]

open access: yesAmerican Journal of Economics and Business Administration, 2011
Problem statement: With the rapid development of World Wide Web (WWW), a huge amount of information is now accessible to the web users. This phenomenon has attracted academic users to publish their research papers online, at the same time downloading and sharing academic papers among them through WWW.
openaire   +1 more source

A lightweight scalable hybrid authentication framework for Internet of Medical Things (IoMT) using blockchain hyperledger consortium network with edge computing

open access: yesScientific Reports
The Internet of Things (IoMT) has revolutionized the global landscape by enabling the hierarchy of interconnectivity between medical devices, sensors, and healthcare applications. Significant limitations in terms of scalability, privacy, and security are
Abdullah Ayub Khan   +6 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

An SDR-Based Satellite Gateway for Internet of Remote Things (IoRT) Applications

open access: yesIEEE Access, 2020
Internet-of-Things (IoT) represents a breakthrough for the current ICT market. In many IoT applications, sensors and actuators are distributed over very wide areas, sometimes not reached by terrestrial networks.
Cristinel Gavrila   +4 more
doaj   +1 more source

Testing the spirit of the information age [PDF]

open access: yes, 2001
Every age has a 'spirit," The Information Age seems to be a more extreme case than most eras, with the constant barrage of messages promising social and individual salvation.
Cox, RJ
core  

Non-classical computing: feasible versus infeasible [PDF]

open access: yes, 2010
Physics sets certain limits on what is and is not computable. These limits are very far from having been reached by current technologies. Whilst proposals for hypercomputation are almost certainly infeasible, there are a number of non classical ...
Cockshott, P.   +2 more
core   +3 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Blockchain-enabled secure Internet of Medical Things (IoMT) architecture for multi-modal data fusion in precision cancer diagnosis and continuous monitoring

open access: yesJournal of Cloud Computing: Advances, Systems and Applications
Advanced precision oncology has the potential to revolutionize the current infrastructure of precision oncology, especially in cancer diagnosis and ongoing monitoring, owing to the strong development and advancement of the Internet of Medical Things ...
Abdullah Ayub Khan   +6 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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