Results 61 to 70 of about 36,382,881 (296)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Blockchain for e-healthcare: a review on secure data management frameworks and future challenges

Journal of Big Data
The revolution in Blockchain Distributed Ledger Technology (BDLT) is changing conventional structures and creating previously unattainable opportunities across a variety of industrial fields.
Abdullah Ayub Khan, Abdullah M. Baqasah, Majed Alsafyani, Hamed Alsufyani, Afnan Alhazmi, Sajid Ullah   +5 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

A novel hybrid transformer-based framework (H-ConvNeXt–Swin) to classify brain tumors using MRI

Scientific Reports
This paper introduces a hybrid deep learning model combining ConvNeXt and Swin Transformer for classifying brain tumors from MRI scans. The ConvNeXt backbone is employed to obtain detailed local spatial features, whereas the Swin Transformer identifies ...
Essam Abdellatef, Rasha M. Al-Makhlasawy, Nesma Abd El-Mawla, Wafaa A. Shalaby   +3 more
doaj   +1 more source

Research trends from computer and electronic sciences

Computer and Electronic Sciences: Theory and Applications, 2020
Electronics as a technical and scientific discipline was born in 1904, based on the principles defined by John Ambrose Fleming (inventor of the diode) and André Marie Ampére (founder of electromagnetic theory), its evolution towards current electronics, has largely been possible thanks to the invention of the triode (device capable of converting ...
openaire   +2 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Using Old Computers for Teaching Computer Science

, 2013
Part 5: Integrating History with Computer Science EducationInternational audienceResearch on the history of computing often needs to adopt experimental archaeology methods: the rebuilding of old hardware and software requires us to proceed by hypothesis ...
Gadducci, Fabio, Cignoni, Giovanni, A.
core   +2 more sources

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Research Progress of Computer in Medicine [PDF]

, 2019
With the rapid development of electronic computers, computer technology has been applied into various fields of medicine and its management. The application of computers in medical treatment has also greatly promoted the development of medical treatment.
Gao Jialin, Zhu Haidong, Haidong Zhu, Jialin Gao   +3 more
core   +2 more sources