Results 41 to 50 of about 181,744 (261)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Consecutive Leakage-Resilient and Updatable Lossy Trapdoor Functions and Application in Sensitive Big-Data Environments

IEEE Access, 2018
Lossy trapdoor functions (LTFs) are very useful tools in constructing complex cryptographic primitives in a black-box manner, such as injective trapdoor functions, collision-resistant hashes, CCA secure public-key encryption, and so on.
Mingwu Zhang, Jiajun Huang, Hua Shen, Zhe Xia, YONG Ding   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

A lightweight scalable hybrid authentication framework for Internet of Medical Things (IoMT) using blockchain hyperledger consortium network with edge computing

Scientific Reports
The Internet of Things (IoMT) has revolutionized the global landscape by enabling the hierarchy of interconnectivity between medical devices, sensors, and healthcare applications. Significant limitations in terms of scalability, privacy, and security are
Abdullah Ayub Khan, Asif Ali Laghari, Roobaea Alroobaea, Abdullah M. Baqasah, Majed Alsafyani, Hamed Alsufyani, Sajid Ullah   +6 more
doaj   +1 more source

An SDR-Based Satellite Gateway for Internet of Remote Things (IoRT) Applications

IEEE Access, 2020
Internet-of-Things (IoT) represents a breakthrough for the current ICT market. In many IoT applications, sensors and actuators are distributed over very wide areas, sometimes not reached by terrestrial networks.
Cristinel Gavrila, Vlad Popescu, Marian Alexandru, Maurizio Murroni, Claudio Sacchi   +4 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Blockchain-enabled secure Internet of Medical Things (IoMT) architecture for multi-modal data fusion in precision cancer diagnosis and continuous monitoring

Journal of Cloud Computing: Advances, Systems and Applications
Advanced precision oncology has the potential to revolutionize the current infrastructure of precision oncology, especially in cancer diagnosis and ongoing monitoring, owing to the strong development and advancement of the Internet of Medical Things ...
Abdullah Ayub Khan, Abdul Khalique Shaikh, Roobaea Alroobaea, Abdullah M. Baqasah, Majed Alsafyani, Hamed Alsufyani, Asif Ali Laghari   +6 more
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source