Results 41 to 50 of about 35,298,032 (247)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Evaluation of the usefulness of a computer‐based learning program to support student learning in pharmacology [PDF]
This study aims to evaluate the effectiveness of a computer‐based teaching program in supporting and enhancing traditional teaching methods. The program covers the pharmacology of inflammation and has been evaluated with a group of second‐year medical ...
A. D. Williams +5 more
core +1 more source
This paper presents a parametric classification methodology to identify common indoor and outdoor furniture objects present in the 3D Cartesian point cloud of the surveyed environment.
Syed Riaz Un Nabi Jafri +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Department of Computer Science newsletter Fall 2023
A Newsletter for Friends and Supporters of the Mines Computer Science ...
core
Facilitating argumentative knowledge construction with computer-supported collaboration scripts [PDF]
Online discussions provide opportunities for learners to engage in argumentative debate, but learners rarely formulate well-grounded arguments or benefit individually from participating in online discussions.
Weinberger, Armin +2 more
core +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Department of Computer Science newsletter 2022
A Newsletter for Friends and Supporters of the Mines Computer Science Department.
core
On the Validation of Computer Science Theories [PDF]
We address normatively the demarcation problem for Computer Science: How can Computer Science research be conducted scientifically? First we attempt to delimit the subject matter of Computer Science, and conclude that it is not computers but programs ...
MacLennan, Bruce J., B. J. MacLennan
core +3 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source

