Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
Multi-site research using electronic health record data: Lessons learned from a case study. [PDF]
Garcia B +4 more
europepmc +1 more source
Summary Introduction Intra‐operative hypotension is common during general anaesthesia, but its association with postoperative pneumonia remains uncertain, partly because hypotension has been defined using different thresholds. We evaluated whether absolute thresholds or relative reductions from baseline mean arterial pressure were associated more ...
Pingping Wang +8 more
wiley +1 more source
A Cloud-Based Platform for Harmonized COVID-19 Data: Design and Implementation of the Rapid Acceleration of Diagnostics (RADx) Data Hub. [PDF]
Martínez-Romero M +17 more
europepmc +1 more source
Effect of Group Prenatal Care Attendance on Gestational Diabetes Mellitus and Preterm Birth
ABSTRACT Introduction Adequate prenatal care is an important tool for achieving optimal health outcomes for both mothers and their babies. A low group prenatal care (GPNC) attendance rate may influence clinical outcomes. We aimed to estimate the effect of GPNC attendance on the risk of gestational diabetes (GDM) and preterm birth (PTB). Methods This is
Roch A. Nianogo +6 more
wiley +1 more source
Beyond Blind Trust in Hospital Data Warehouses: Evaluating Real-World Data Accountability. [PDF]
Morohashi A +6 more
europepmc +1 more source
Gender stereotypes in preschool: An examination of age and gender differences
Abstract Gender stereotypes are prevalent in many societies and begin to emerge in early childhood. The present study examined the gender stereotypes and their association with age and gender in preschool. Gender stereotypes of feminine, masculine and gender‐neutral traits and behaviours were collected in a sample of 104 German and Austrian children ...
Johanna Landvogt, Jan Lenhart
wiley +1 more source
Toward a Candidate Endoscopic Spine Surgery Registry Framework: Lessons From Global Spine Registry Models. [PDF]
Kotheeranurak V +11 more
europepmc +1 more source
Perioperative Durvalumab for Resectable NSCLC: Updated Outcomes for Japanese Patients in AEGEAN
In prespecified exploratory analyses of Japanese patients with resectable NSCLC enrolled in the AEGEAN trial, perioperative durvalumab plus neoadjuvant chemotherapy demonstrated clinically meaningful improvements in the primary endpoints of EFS and pCR versus neoadjuvant chemotherapy alone.
Tetsuya Mitsudomi +16 more
wiley +1 more source
A flexible framework for automated STED super-resolution microscopy. [PDF]
Hörl D.
europepmc +1 more source

