Results 61 to 70 of about 5,108,326 (341)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The detection of patients at risk of gastrointestinal toxicity during pelvic radiotherapy by electronic nose and FAIMS : a pilot study [PDF]

, 2012
It is well known that the electronic nose can be used to identify differences between human health and disease for a range of disorders. We present a pilot study to investigate if the electronic nose and a newer technology, FAIMS (Field Asymmetric Ion ...
Ouaret, N., Arasaradnam, Ramesh P., Linda Wedlake, Andreyev, J., Jervoise Andreyev, James A. Covington, Chuka U. Nwokolo, Matthew G. Thomas, Covington, James A., Nathalie Ouaret, Thomas, Matthew G., Wedlake, L., Nwokolo, Chuka U., Ramesh P. Arasaradnam, Bardhan, Karna Dev, Karna D. Bardhan   +15 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Strain-Modulated Electronic Transport Properties in Two-Dimensional Green Phosphorene with Different Edge Morphologies

Crystals
Based on two-dimensional green phosphorene, we designed two molecular electronic devices with zigzag (Type 1) and whisker-like (Type 2) configurations.
Shuo Li, Hai Yang
doaj   +1 more source

Differential Microscopy by Electron Holography With an Electron Trapezoidal Prism

Microscopy and Microanalysis, 1997
Abstract Electron holography has been successfully used in the observation of phase objects such as magnetic fields and electrostatic potentials. Electron holograms are constructed by the interference of a modulated object wave and a well-defined reference wave and in most cases the reference wave is required to be a plane wave ...
T Tanji, S Manabe
openaire   +1 more source

Differential cross sections for electron impact excitation of the electronic bands of phenol [PDF]

The Journal of Chemical Physics, 2015
We report results from a joint theoretical and experimental investigation into electron scattering from the important organic species phenol (C6H5OH). Specifically, differential cross sections (DCSs) have been measured and calculated for the electron-impact excitation of the electronic states of C6H5OH.
R. F. C. Neves, D. B. Jones, M. C. A. Lopes, K. L. Nixon, G. B. da Silva, H. V. Duque, E. M. de Oliveira, R. F. da Costa, M. T. do N. Varella, M. H. F. Bettega, M. A. P. Lima, K. Ratnavelu, G. García, M. J. Brunger   +13 more
openaire   +6 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

AN ELECTRON MICROSCOPY OF THE RENAL DIFFERENTIATION

The Keio Journal of Medicine, 1959
1) The author has observed by electron microscope the glomerular differentiation of rats.2) Glomerular capillary is formed by the glomerular anlage cells which appear beneath the inner layer of the metanephrogenic vesicle.3) Glomerular anlage cells proliferate immediately below the inner layer and form intercellular space and later on blood' cavities ...
openaire   +3 more sources

Active Power Criterion Based High-Adaptive Differential Protection for Power Electronic Equipment

Energies
In flexible AC/DC microgrids, a variety of non-traditional power equipment are in operation, such as AC/DC interlinking converters. Moreover, due to the influence of interlinking converters, short-circuit fault characteristics in microgrids are much ...
Yigong Xie, Chen Wu, Min Cheng, Dan Zhang, Xiao Zhang, Qian Chen   +5 more
doaj   +1 more source

Differential detection of potentially hazardous Fusarium species in wheat grains by an electronic nose. [PDF]

PLoS ONE, 2011
Fungal infestation on wheat is an increasingly grave nutritional problem in many countries worldwide. Fusarium species are especially harmful pathogens due to their toxic metabolites. In this work we studied volatile compounds released by F. cerealis, F.
Jakob Eifler, Eugenio Martinelli, Marco Santonico, Rosamaria Capuano, Detlev Schild, Corrado Di Natale   +5 more
doaj   +1 more source