Results 31 to 40 of about 808,924 (309)

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Scientific journals, overlays and repositories: a case study of costs and sustainability issues [PDF]

open access: yes, 2008
Publishing scientific research is an area of study that attracts interest from various stakeholders such as publishers, academic and research staff, libraries and funders.
Moyle, M., Polydoratou, P.
core   +1 more source

A molecular proximity sensor based on an engineered, dual-component guide RNA

open access: yeseLife
One of the goals of synthetic biology is to enable the design of arbitrary molecular circuits with programmable inputs and outputs. Such circuits bridge the properties of electronic and natural circuits, processing information in a predictable manner ...
Junhong Choi   +4 more
doaj   +1 more source

Paradigm Lost? Electronic Publishing and the Renewal of Research

open access: yesDigital Studies, 1998
None
Pascal Michelucci, Peter Marteinson
doaj   +1 more source

Electronic Dance Music in Narrative Film [PDF]

open access: yes, 2019
As a growing number of filmmakers are moving away from the traditional model of orchestral underscoring in favor of a more contemporary approach to film sound, electronic dance music (EDM) is playing an increasingly important role in current soundtrack ...
Filoseta, Roberto
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

'Nenhum Problema Tem Solução': Um Arquivo Digital do Livro do Desassossego

open access: yesMatLit, 2013
The research project 'No Problem Has Solution: A Digital Archive of the Book of Disquiet' aims to produce a digital hypermedia archive of the Book of Disquiet [LdoD], by Bernardo Soares/Fernando Pessoa.
Manuel Portela
doaj   +1 more source

THE TRANSLATION QUALITY PROBLEMS OF MACHINE TRANSLATION SYSTEMS FOR THE KAZAKH LANGUAGE

open access: yesВестник КазНУ. Серия математика, механика, информатика, 2021
Kazakh language is related to languages with complex morphology and syntax. Today, most machine translation systems consider Kazakh language too, like Google, Yandex, Prompt, etc.
A. Karibayeva   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy