Results 71 to 80 of about 788,887 (309)

Zebrafish small molecule screens: Taking the phenotypic plunge

open access: yesComputational and Structural Biotechnology Journal, 2016
Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency.
Charles H. Williams, Charles C. Hong
doaj   +1 more source

Coping with a changing world: the UK Open University approach to teaching ICT [PDF]

open access: yes, 2008
The rapid pace of change in the ICT field has affected all HE providers, but for the UK Open University (UKOU), used to print-based courses lasting eight years or more, it has been a particular challenge. This paper will present some of the ways the UKOU
Bissell, C C, Williams, J P
core   +1 more source

Long‐Term Opioids in Gout: A Matched Cohort Study From the Veterans Health Administration

open access: yesArthritis Care &Research, EarlyView.
Objective Though used frequently to treat flare, risk of long‐term opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed long‐term opioids over time.
Lindsay N. Helget   +7 more
wiley   +1 more source

Economic Burden of Rheumatoid Arthritis in Low‐ and Middle‐Income Countries: Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this systematic review was to synthesize the economic impact of rheumatoid arthritis (RA) on households, health systems, and society in low‐ and middle‐income countries (LMICs). Methods Electronic databases such as PubMed, Web of Science, and CINAHL were searched using keywords related to RA and cost of illness.
Tadesse Gebrye   +6 more
wiley   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records From an Integrated Health System

open access: yesArthritis Care &Research, EarlyView.
Objective This study aims to describe the frequency and timing of physician referrals to physical therapists (PTs) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja   +4 more
wiley   +1 more source

XML views for electronic editions

open access: yesProceedings of the 6th ACM/IEEE-CS joint conference on Digital libraries, 2006
In this paper we discuss the implementation of user-defined views over multihierarchical document-centric XML documents.
Iacob, Ionut E., Dekhtyar, Alex
openaire   +3 more sources

Research Report - October 2009. Elaboration of the Module: Definition of the Programme [PDF]

open access: yes, 2009
Alternative innovative didactic methodology is needed to reduce premature school drop out,particularly of young people at risk of exclusion, such as migrants, ethnic groups and children/teenagers from difficult socio-economic background).
Miranda , E., Troisi, Anna
core  

Trail records and navigational learning [PDF]

open access: yes, 2003
An emerging wave of 'ambient' technologies has the potential to support learning in new and particular ways. In this paper we propose a 'trail model' of 'navigational learning' which links some particular learning needs to the potentialities of these ...
Levene, Mark, Peterson, Don
core   +1 more source

Prevalence, Determinants, and Outcomes of Low Disease Activity and Remission Attainment in Patients With Systemic Lupus Erythematosus That Is Clinically Active

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to identify in patients with systemic lupus erythematosus (SLE) with clinically active disease the attainment of frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS) and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao   +39 more
wiley   +1 more source

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