Results 101 to 110 of about 3,780,566 (296)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Mie resonances and bonding in photonic crystals

, 1997
Isolated dielectric spheres support resonant electromagnetic modes which are analogous to electronic orbitals and, like their electronic counterparts, can form bonding or anti-bonding interactions between neighbouring spheres.
Bohren C. F., Cheng C. C., Israelachvili J. N., Israelachvili J. N., J. B Pendry, Kafesaki M., M. I Antonoyiannakis, Mahanty J., Mie G., Pendry J. B., Pendry J. B., Soukoulis C. M. (Editor), Stefanou N., Sözüer H. S.   +13 more
core   +2 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

The Wording of a Contract in Electronic Form

Legal Concept, 2019
Introduction: in the modern economy, registering the wording of a contract with the help of electronic documents has acquired the character of a stable trend. The aim of the study is to identify the main trends in the practice of exchanging electronic documents for the conclusion or execution of a civil contract.
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Recent Experimnts on Forming Electron Rings at Berkeley

IEEE Transactions on Nuclear Science, 1971
In the initial electron-ring experiments with a new high-current, 2 MeV electron injector an efficient method of trapping of the injected beam was developed, and a suitable compression cycle was found in which betatron amplitude growth on single-particle resonances is negligible.
Lambertson, G.R., Keefe, D., Laslett, L.J., Perkins, W.A., Peterson, J.M., Rechen, J.B.   +5 more
openaire   +2 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Adverse effects of electronic cigarette vapor condensation on oral cells: A scoping review

Revista Contexto & Saúde
Electronic cigarettes (ECs), when internally heated, generate aerosol through e-liquid, with part of it being absorbed into the bloodstream. Consequently, little is known about the potential adverse events of this vapor on oral cells, which may ...
Zildenilson da Silva Sousa, Rafael César da Silva Oliveira, Caroline Mary Gurgel Dias Florêncio, Ana Vitória Machado Duarte, Moysés Matias Mateus, Sara Liz Sales Moreira, Thallyta Victoria Bandeira Moreira, Raissa Pinheiro Moraes   +7 more
doaj   +1 more source

Two-Loop QCD Corrections to the Heavy Quark Form Factors: Axial Vector Contributions

, 2004
We consider the Z Q Qbar vertex to second order in the QCD coupling for an on-shell massive quark-antiquark pair and for arbitrary momentum transfer of the Z boson.
't Hooft, Aguilar-Saavedra, Bernreuther, Bonciani, Bonciani, Bonciani, Bonciani, Broadhurst, Caffo, Caffo, Chetyrkin, E. Remiddi, Freitas, Gehrmann, Gehrmann, Jersak, Jersak, Kotikov, Kühn, Laporta, Laporta, Larin, Melnikov, P. Mastrolia, R. Bonciani, R. Heinesch, Remiddi, Remiddi, T. Gehrmann, T. Leineweber, Tkachov, Vermaseren, Vermaseren, W. Bernreuther   +33 more
core   +2 more sources