Results 21 to 30 of about 239,391 (257)

Mapping the Network Relationships of Strategic Damage of Electronic Government Development in Iran [PDF]

مطالعات مدیریت کسب و کار هوشمند, 2019
The focus on the establishment and development of electronic government in Iran is one of the serious plans of all governments in the Islamic Republic.
Hadi Khan Mohammadi, Iman Raeesi Vanani, Sahar Malek Mohammadi   +2 more
doaj   +1 more source

Interoperability frameworks for electronic governance

Proceedings of the 2nd international conference on Theory and practice of electronic governance, 2008
Today, there is a growing awareness that the interoperability of national public information and communication technology (ICT) infrastructures is a precondition for a more service-oriented and competitive public sector. Interoperability means the ability of ICT systems and of business processes they support to exchange data and to enable the sharing ...
Alejandra Cechich, Lorenzo Madrid, Jeremy Gibbons, Jay P. Kesan   +3 more
openaire   +2 more sources

Informatica giuridica per le pubbliche amministrazioni. Gli appalti pubblici informatici [Legal information technology for public administrations. Public IT procurement]

Open Journal of Humanities, 2022
The term e-procurement indicates a set of technologies, procedures, operations and organizational methods that allow the acquisition of goods or services online, thanks to the possibilities offered by the Internet and electronic commerce.
Wanda D'Avanzo
doaj   +1 more source

Semantic technologies in electronic government

Proceedings of the 2nd international conference on Theory and practice of electronic governance, 2008
Joined-up government depends fundamentally on semantics --- on the computable representation of meaning, so that data is associated with appropriate metadata from the start, and this association is maintained as the data is manipulated. This paper summaries a tutorial and workshop on semantic technologies for supporting electronic government.
Steve Harris, Jeremy Gibbons, Jim Davies, Andrew Tsui, Charles Crichton   +4 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

The Organizational and Methodological Aspects of Remotely Researching the Issues Arising from the Digital Transformation of Regions with Different Levels of Social and Cultural Modernization. Part I

Социологическая наука и социальная практика, 2019
This is the first part of an article that will discuss digital transformation issues in Russian regions that differ by social and cultural modernization level, as well as the population’s willingness to accept digital transformation in life and at work ...
Vladimir S. Bogdanov
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source