Results 211 to 220 of about 22,523 (262)

Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Exercise modalities and outcome measures used in older adults after hip fracture with or without signs of cognitive impairment: a national cross-sectional e-survey of 90 out of 98 municipalities in Denmark. [PDF]

J Rehabil Med
Overgaard JA, Kristensen MT, Beaupre LA, Frederiksen KS, Skou ST.   +4 more
europepmc   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Municipal multidimensional poverty increases the risk of acute myocardial infarction: a retrospective cohort study with sex-stratified analyses in Chile's public health system. [PDF]

BMJ Open
Bello-Escamilla N, Pino P, Nazzal C.
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Supply chain management of health commodities and essential drug procurement systems at Sankhuwasabha and Kavrepalanchowk districts of federal Nepal. [PDF]

J Public Health Res
Sharma RK, Kumari M, Baxi R.
europepmc   +1 more source

Effects of a patient-controlled analgesia pump management model based on a wireless analgesic management system on postoperative pain management in orthopedic patients: a prospective randomized controlled trial protocol. [PDF]

Perioper Med (Lond)
Zhang D, Yu C, Kang J, Guo L, Zheng C, Wang J, Li X.   +6 more
europepmc   +1 more source

Implementing Electronic Participatory Budgeting in Swedish Municipalities

, 2010
openaire   +1 more source

Scaling Up a Diabetes Prevention Program in Geographically and Ethnoculturally Diverse Urban Regions of Canada: Protocol for a Hybrid Type 2 Implementation-Effectiveness Study. [PDF]

JMIR Res Protoc
Weatherson K, Bourne JE, Cranston K, Braaten K, Grieve N, Kelly J, Jung ME.   +6 more
europepmc   +1 more source

Measles-rubella surveillance and its facilitators and barriers in Bagmati province, Nepal: a mixed methods study. [PDF]

BMC Infect Dis
Shrestha B, Kunwar S, Upreti A, Karki K, Pangeni P, Subedi P, Khanal L, Shrestha R, Tamrakar D, Tinkari BS, Upreti SR.   +10 more
europepmc   +1 more source