Results 111 to 120 of about 6,816,634 (243)

NSD2 Coordinates the Neurogenic‐to‐Gliogenic Transition via H3K36me2‐Dependent Activation of the EGFR‐ERK Pathway

Advanced Science, EarlyView.
NSD2 coordinates the neurogenic‐to‐gliogenic transition in the developing neocortex through H3K36me2‐dependent activation of EGFR–ERK signaling. Loss of NSD2 disrupts astroglial and oligodendroglial development, whereas ERK activation rescues gliogenic defects in vitro and in vivo.
Hanxue Chen, Mengyuan Li, Lin Hou, Bin Yin, Boqin Qiang, Ran Gao, Pengcheng Shu, Xiaozhong Peng   +7 more
wiley   +1 more source

A Novel Electronic Nose Using Biomimetic Spiking Neural Network for Mixed Gas Recognition

Chemosensors
Odors existing in natural environment are typically mixtures of a large variety of chemical compounds in specific proportions. It is a challenging task for an electronic nose to recognize the gas mixtures.
Yingying Xue, Shimeng Mou, Changming Chen, Weijie Yu, Hao Wan, Liujing Zhuang, Ping Wang   +6 more
doaj   +1 more source

Single‐Atom‐Enhanced Fully Inkjet‐Printed Electrochemical Sensor for Dopamine Detection

Advanced Science, EarlyView.
Fully inkjet‐printed paper‐based dopamine sensors are fabricated using nitrogen‐doped graphene acid functionalized with copper single atoms. The copper sites uniquely enhance dopamine oxidation through strong molecular adsorption, as verified by electrochemical measurements and DFT calculations. The approach highlights the potential of single‐atom inks
Martin‐Alex Nalepa, David Panáček, Vítězslav Hrubý, Matěj Jendrišák, Rostislav Langer, Michal Langer, Petr Jakubec, Ivan Dědek, Vojtěch Kupka, Michal Mazur, Radek Zbořil, Michal Otyepka   +11 more
wiley   +1 more source

A Rigid–Foldable Kirigami‐Inspired Metamorphic Mechanism With Programmable Motion Modes and Self‐Locking

Advanced Science, EarlyView.
Geometric constraint reconfiguration enables a rigid–foldable kirigami‐inspired mechanism to switch between twisting, directional translation, and self‐locking states. By encoding multifunctionality directly into its architecture, the mechanism achieves multimodal motion and passive locking without reassembly, providing a compact platform for adaptive ...
Jianlin Wang, Zhongmin Song, Ketao Zhang
wiley   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Dual Lineages of Langerhans Cells Cooperate to Restore the Immune Barrier after Skin Injury

Advanced Science, EarlyView.
After skin injury, the epidermal immune barrier is rebuilt by two sources of Langerhans cells. Resident Langerhans cells first move into the wound during re‐epithelialization, guided by CXCR2 signaling. Later, recruited monocytes become long‐lived Langerhans cells.
Axel D. Schmitter‐Sánchez, Nicholas Basista, Sudhanshu Mishra, Hyeri Kim, Audrey Bench, Catherine Matte‐Martone, Min‐Soo Seo, Gun Woo Lee, Sangbum Park   +8 more
wiley   +1 more source

Bending‐Stable Pressure Sensor Based on Natural Wood Nanofibers for Ultra‐Low Detection Limit

Advanced Science, EarlyView.
A wood nanofiber‐based flexible pressure sensor with intrinsic bending‐stable performance is developed through a porous electrospun architecture and interdigital electrode design. The device exhibits an ultra‐low detection limit and stable operation under deformation for physiological monitoring and spatial sensing, providing a sustainable strategy for
Xu Zeng, Zhengnan Sun, Yilin Wang, Yao Tan, Ranran Xu, Beomjoon Kim, Juergen Brugger, Xiaosheng Zhang   +7 more
wiley   +1 more source

Intranasal Delivery of Gallium–Quercetin Nanoparticles for Multi‐Target Ferroptosis Inhibition in Parkinson's Disease

Advanced Science, EarlyView.
Leveraging the chemical similarity between Ga3+ and Fe3+ as well as the antioxidant properties of quercetin, gallium–quercetin nanoparticles (GQNPs) were prepared to integrate iron homeostasis regulation, oxidative stress suppression, and mitochondrial protection for multi‐target ferroptosis inhibition in Parkinson's Disease.
Keyang Xu, Dandan Kou, Xiao Xiao, Bingbing Bai, Caide Liu, Mengyao Wu, Yadan Shi, Mengdan Xu, Xiaoyi Cao, Haodi Qi, Shuhua Wu, Jianfeng Zeng, Mingyuan Gao   +12 more
wiley   +1 more source

Authenticity verification and fraud detection in turmeric powder based on aroma and taste profiles using electronic nose, electronic tongue and artificial intelligence

Results in Chemistry
Spices are usually the most widely used ingredients in the food industry, which are sold in bulk and powdered form in the market, and the possibility of adulterating them is very high.
Ahmad Jahanbakhshi, Yousef Abbaspour-Gilandeh, Kobra Heidarbeigi, Mahmoud Roushani, Mohammad Momeny   +4 more
doaj   +1 more source

Harnessing Li‐Ion Binding Energy for Solvation‐Guided Electrolyte Additive Design and Robust Solid Electrolyte Interphase Reinforcement

Advanced Science, EarlyView.
A solvation‐guided design strategy for electrolyte additives is established, identifying Li‐ion binding energy as a crucial determinant for effective interface reinforcement. ABSTRACT The rational design of electrolyte systems is essential for stabilizing the electrode−electrolyte interface to enhance the electrochemical performance of lithium‐ion ...
Jooeun Byun, Ho Yeon Jang, Myung‐Jun Kwak, Chae Rim Lee, Chihyun Hwang, Seoin Back, Hyun‐seung Kim   +6 more
wiley   +1 more source