Results 71 to 80 of about 2,392,943 (401)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Dataset for Electronics and Plasmonics in Graphene, Silicene, and Germanene Nanostrips

Data
The quest for novel materials with extraordinary electronic and plasmonic properties is an ongoing pursuit in the field of materials science. The dataset provides the results of a computational study that used ab initio and semi-analytical computations ...
Talia Tene, Nataly Bonilla García, Miguel Ángel Sáez Paguay, John Vera, Marco Guevara, Cristian Vacacela Gomez, Stefano Bellucci   +6 more
doaj   +1 more source

One‐Step 3D Printing of Heart Patches with Built‐In Electronics for Performance Regulation

Advanced Science, 2021
Three dimensional (3D) printing of heart patches usually provides the ability to precisely control cell location in 3D space. Here, one‐step 3D printing of cardiac patches with built‐in soft and stretchable electronics is reported.
Masha Asulin, Idan Michael, Assaf Shapira, Tal Dvir   +3 more
doaj   +1 more source

Silicon-based molecular electronics

, 2003
Molecular electronics on silicon has distinct advantages over its metallic counterpart. We describe a theoretical formalism for transport through semiconductor-molecule heterostructures, combining a semi-empirical treatment of the bulk silicon ...
Berkowitz H. L., Büttiker M., Chen C. J., Coulter S. K., Damle P. S., Datta S., Datta S., Emberly E. G., Frisch M. J., Ghosh A. W., Guisinger N., Guisinger N., Hamers R. J., Hofer W. A., Kubatkin S., Liu Q., Lundstrom M., Lyo I-W, Mathews R. H., McEllistrem M., Reed M. A., Sze S. M., Vogl, Wolkow R. A., Zhu X.-Y.   +24 more
core   +1 more source

Solidifying Power Electronics [Historical] [PDF]

, 2018
More than one century ago, in 1902, American engineer Peter Cooper Hewitt (1861\u20131921) derived the mercury arc-rectifier, enclosed in a glass bulb, from his mercury-vapor lamp of the previous year.
Guarnieri, Massimo
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

THE INFLUENCE OF LEARNING OUTCOMES PRODUCTIVE SUBJECTS AND SELF-RELIANCE LEARNING WITH ACHIEVEMENT INDUSTRIAL WORK PRACTICES STUDENTS OF GRADE XII ELECTRONICS ENGINEERING SKILLS PROGRAM AT SMKN 3 YOGYAKARTA ACADEMIC YEAR 2012/2013 [PDF]

, 2013
This study aimed to determine: (1) the influence of Learning Outcomes Productive Subjects with Achievement Industrial Work Practices students of grade XII Electronics Engineering Skills Program at SMKN 3 Yogyakarta Academic Year 2012/2013.
Afni Nur, Anita
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Software Emulation of a Hardware Voice Synthesiser

Fields, 2019
The aim of this project was to develop a fully functional emulator of the Speech Plus CallText 5010 hardware voice synthesiser used by Professor Stephen Hawking. Successful completion of the project would allow him to preserve his voice and would greatly
Pawel Wozniak
doaj   +2 more sources

G$^0$ Electronics and Data Acquisition (Forward-Angle Measurements) [PDF]

, 2007
The G$^0$ parity-violation experiment at Jefferson Lab (Newport News, VA) is designed to determine the contribution of strange/anti-strange quark pairs to the intrinsic properties of the proton.
Arvieux, J., Bimbot, L., Biselli, A., Bouvier, J., Breuer, H., Clark, R., Cuzon, J. -C., Engrand, M., Foglio, R., Furget, C., Grave, X., Guillon, B., Guler, H., King, P. M., Kox, S., Kuhn, J., Ky, Y., Lachniet, J., Lenoble, J., Liatard, E., Liu, J., Marchand, D., Munoz, E., Pouxe, J., Quinn, B., Quéméner, G., Rossetto, O., Réal, J. -S., Sellem, R.   +28 more
core   +4 more sources