Results 191 to 200 of about 101,786 (260)

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Tuning Apparent Peak Efficiency in Capillary Electrophoresis Using Backscatter Interferometry Detection. [PDF]

Electrophoresis
De Silva M, Kariuki SM, Dunn RC.
europepmc   +1 more source

Development of a High‐Throughput Microarray Platform for Rapid, Low‐Cost Expanded Carrier Screening

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To develop a customized expanded carrier screening (ECS) solution for 8271 variants of 265 genes. Based on a microarray platform, this solution demonstrates comparable accuracy to next‐generation sequencing (NGS) platform; however, it has a lower cost, a faster speed, and a simplified data—analysis process.
Jiazhen Chang, Na Hao, Xiya Zhou, Yan Lü, Mengmeng Li, Kaili Yin, Xueting Yang, Hanzhe Zhang, Yukun Ma, Yanqin You, Qingwei Qi, Yulin Jiang   +11 more
wiley   +1 more source

A Sustainable CE-DAD Screening Method for Multi-Class Polyphenol Profiling in Rosehip-Based Herbal Tea and Supplement. [PDF]

Foods
Simonetti G, Buiarelli F, Astolfi S, Candiano F, Fricano A, Presutti M, Riccardi C, Pomata D, Di Filippo P.   +8 more
europepmc   +1 more source

Novel and High‐Throughput Method of Isolating Single Fetal Cells Using FACS for NIPT

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate fluorescence activated cell sorting (FACS) as a method of single‐cell isolation of rare circulating fetal cells from maternal blood for use in cell‐based non‐invasive prenatal testing (cbNIPT). Method Blood samples (30 mL) were collected from 75 ‘low‐risk’ pregnant women (gestational age 10–15 weeks).
Ripudaman Singh, Bolette Hestbek Nicolaisen, Mathias Kølvraa, Inga Baasch Christensen, Mads Tang Dalsgaard, Lars Henning Pedersen, Niels Uldbjerg, Ida Vogel, Lotte Hatt, Katarina Ravn   +9 more
wiley   +1 more source

Human Umbilical Cord Mesenchymal Stem Cell‐Derived Microvesicles Alleviate Bronchopulmonary Dysplasia in Preterm Rats by Inhibiting Neutrophil Extracellular Trap Formation

Pediatric Discovery, EarlyView.
Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu, Wen Tan, Xiao Yang, Tingting Luo, Chenghao Mei, Huaqin Bu, Jinhua Ma, Chao Gong, Li Zhong, Ou Zhou, Daiyin Tian   +10 more
wiley   +1 more source

In Situ Analytical Chemistry Laboratory for the Exobiology Extant Life Surveyor. [PDF]

ACS Meas Sci Au
Drevinskas T, Cable ML, Stenner C, Gardner AS, Paton M, Malaska MJ, Cruz S, Rieber R, Etheredge R, Robinson M, Ono M, Mora MF, Bagshaw EA, Prior-Jones MR, Ferreira Santos MS, Noell AC, Willis PA.   +16 more
europepmc   +1 more source

Machine learning-based cfDNA fragmentation profiling using automated capillary electrophoresis for early detection of hepatocellular carcinoma. [PDF]

Commun Med (Lond)
Udomruk S, Sutthitthasakul S, Bunsermvicha N, Pinyopornpanish K, Pruksakorn D, Charoenkwan P, Yongpitakwattana P, Khounkaew K, Jaimalai T, Duangsan T, Orrapin S, Moonmuang S, Noisagul P, Pasena A, Suksakit P, Gamngoen R, Teeyakasem P, Charoentum C, Kongkarnka S, Lapisatepun W, Chaiyawat P.   +20 more
europepmc   +1 more source

A Novel Alpha1-Variant (HBA1:c.-35T>C) Complexed With the First Reported Hb M-Saskatoon in the Chinese Population. [PDF]

Mol Genet Genomic Med
Yang Y, Zhao Y, Luan L, Li G, Deng Q, Ge Y.   +5 more
europepmc   +1 more source

Successful 6-year follow-up of treatment for IgA nephropathy complicated by IgA-λ monoclonal gammopathy with multi-system damage: a case report. [PDF]

Front Immunol
Li Y, Li X, Lu Y, Huang M.
europepmc   +1 more source