Results 171 to 180 of about 228,742 (299)

UGT1A1 Fragment Analysis: Genotyping the (TA)n Variable Repeat Polymorphism for Clinical Applications

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a PCR‐based fragment analysis assay for UGT1A1 rs3064744 targeting TA5 (*36), TA6 (*1), TA7 (*28), and TA8 (*37). The assay was CLIA validated with data showing 100% concordance and a sensitivity of 0.5 ng/uL. The assay was then implemented in a patient cohort of n = 940 and the results compared with PharmacoScan.
Ryan N. Baugher, Kristen M. Pike, Teri M. Plona, Stephanie D. Mellott, Todd B. Young, Heidi E. Lawhorn, Stephen M. Hewitt   +6 more
wiley   +1 more source

Common hemoglobin variants affecting the diagnosis of β-thalassemia: A large cohort data at a single center. [PDF]

PLoS One
Singha K, Srivorakun H, Yamsri S, Chaibunruang A, Pansuwan A, Changtrakul Y, Sanchisuriya K, Fucharoen G, Fucharoen S.   +8 more
europepmc   +1 more source

Exploring supported ionic liquids for IgY antibody purification

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Immunoglobulin Y (IgY), a scalable alternative to mammalian antibodies, typically found in hen's egg yolk, has gained attraction in diagnostic and therapeutic applications. However, its purification from egg yolk remains challenging due to the complex matrix and limitations of conventional techniques. Supported Ionic Liquids (SILs),
Amanda RP Silva, Catarina Almeida, Márcia C Neves, Carlota O Rangel‐Yagui, Mara G Freire   +4 more
wiley   +1 more source

A Novel Aberrant HbF Peak with Electrophoretic Shift in A1c of a Patient with Chronic Lymphocytic Leukemia (CLL) Was Reversible to Give Interpretable Results. [PDF]

Biomedicines
Obrenovich ME, Schroer EA, Li Y, Quam R, Munoz A, Khan S.   +5 more
europepmc   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Proteoform-Resolved Interaction Studies of Plasminogen by CZE-MS and SEC-MS Under Near-Native Conditions. [PDF]

J Mass Spectrom
Neusüß C, Lioe H, Dite T, Ow S, Pelzing M.   +4 more
europepmc   +1 more source

Ginsenoside Rg1 Ameliorates LPS‐Induced Sepsis‐Associated Lung Injury in Mice via VEGFC/D‐VEGFR3 Signaling‐Mediated Lymphangiogenesis and Lymphatic Remodeling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang, Lan Hu, Chun‐Pan Zhang, Wen‐Jie Qi, Yu‐Guo Song   +4 more
wiley   +1 more source

PCR Product Cleanup Methods for Capillary Electrophoresis

BioTechniques, 2003
Darryl L. Irwin, Keith R. Mitchelson, Ian Findlay   +2 more
doaj   +1 more source

Recent Developments and Applications of Capillary and Microchip Electrophoresis in Proteomics and Peptidomics (2023-2025). [PDF]

J Sep Sci
Štěpánová S, Kašička V.
europepmc   +1 more source

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source