This study develops a novel miRNA‐based framework for estimating the time since deposition of semen stains, combining small RNA sequencing with machine learning. Time‐dependent miRNA modules were identified using Mfuzz clustering and WGCNA, followed by a multi‐stage feature selection pipeline that reduced 261 candidate miRNAs to a minimal 7‐miRNA panel.
Meiming Cai +11 more
wiley +1 more source
Screening method for detection of genetically modified soybean and maize events using multiplex PCR combined with capillary electrophoresis. [PDF]
Park S, Lee SG, Shin K.
europepmc +1 more source
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang +4 more
wiley +1 more source
Beyond Iron Deficiency: An Atypical Peripheral Smear Revealing Hemoglobin C in an Adolescent. [PDF]
Hamidine M, Awati M, Mehdi A.
europepmc +1 more source
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez +6 more
wiley +1 more source
First clinical and molecular characterization of two rare complex β-globin variants in Chinese population using third generation sequencing. [PDF]
Zhang L +4 more
europepmc +1 more source
Capillary electrophoresis and capillary electrophoresis-mass spectrometry in catecholamine studies [PDF]
Vuorensola, Katariina
core
Calreticulin Type 26 Mutation in Myelofibrosis: A Rare Variant With Diagnostic Challenges
ABSTRACT Background Myeloproliferative neoplasms (MPNs) are clonal hematologic disorders commonly driven by mutations in JAK2, MPL, or CALR. Because routine CALR assays are largely optimized for the canonical Type 1 and Type 2 exon 9 variants, rare noncanonical mutations may be missed, creating diagnostic challenges.
Teresa Maltese +6 more
wiley +1 more source
Molecular and Clinical Characterization of the Hb Tübingen [β106(G8) Leu→ Gln, HBB: c.320 T>A] Associated With Congenital Methemoglobinemia in a Chinese Family. [PDF]
Luo H +7 more
europepmc +1 more source

