Results 141 to 150 of about 125,873 (309)
Advanced Analytical Methods for Pharmaceutical and Diagnostic Applications
CHIMIA, 1997 Driving forces for the development of novel analytical technologies in the life-science industry are described. Technologies which either were developed in Bio-Analytical Research or brought to a reliability required for routine applications ...
Markus Ehrat +4 more
doaj +2 more sources
Developmental Dynamics, EarlyView.Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff +6 more
wiley +1 more source
ELECTROPHORESIS, EarlyView.Inhibition assays in in‐capillary continuous enzymatic reaction were simulated using a MATLAB matrix. The enzymatic hydrolysis of p‐nitrophenyl phosphate (S) with alkaline phosphatase (ALP) was adopted as a model enzymatic reaction, where theophylline (I) was used as a model inhibitor.
Toshio Takayanagi +2 more
wiley +1 more source
Enantiomer separation of disopyramide with capillary electrophoresis using various cyclodextrins
, 1997 Enantiomers of disopyramide display different biological actions, and therefore chiral selective analysis is necessary. Fifteen different cyclodextrins (CDs) and CD derivatives were tested as capillary electrophoresis (CE) additives for the chiral ...
Markides, KE, Juvancz, Z,, Jicsinszky, L
core
Desenvolvimento e validação de método rápido para determinação simultânea de nitrato e nitrito em alimentos infantis utilizando eletroforese capilar [PDF]
, 2014 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias, Programa de Pós-Graduação em Ciência dos Alimentos, Florianópolis, 2014.Este estudo propõe um método rápido e inovador para determinação simultânea de nitrato e
Della Betta, Fabiana
core
Optimized iCIEF Fractionation Enables Deep Profiling of Antibody Drug Conjugate Charge Heterogeneity
ELECTROPHORESIS, EarlyView.This study developed and optimized an iCIEF fractionation method to characterize ADC charge variants. The optimized approach enabled stable separation, identification of major PTMs, and drug‐load distributions across light and heavy chains. ABSTRACT Antibody drug conjugates (ADCs) are a novel class of therapeutic drugs that combine selectivity of an ...
Eunju Jang +2 more
wiley +1 more source
ELECTROPHORESIS, EarlyView.A CE‐C4D method was developed for the indirect determination of flunixin meglumine (FM) by quantifying meglumine and using lithium ions as an internal standard. The method allows the use of a low‐cost standard reagent, providing suitable analytical performance for the determination of FM in veterinary pharmaceutical formulations.
Letícia M. de Araujo +2 more
wiley +1 more source
Capillary zone elactrophoresis of hydroxynitrile lyase and b-glucosidase from sweet almond [PDF]
, 1996 The extract from defatted almond meal, called emulsin, contains b-glucosidases and oxynitrilases. Oxinitrilase catalyzes the formation of chemical equilibrium between a-hydroxynitriles and their corresponding aldehydes and HCN.
M. Chiari, D. Tura, S. Riva
core
ELECTROPHORESIS, EarlyView.Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley +1 more source
ELECTROPHORESIS, EarlyView.A green CZE–UV alternative method for quantifying SCFAs in human stool with cost‐effective and automatization, informative data about patients through reduced sample preparation and minimal consumable. CE is simple and robust equipment for routine clinical laboratory workflows, supporting physicians with information that enhances the accuracy of ...
Olívia B. O. Moreira +6 more
wiley +1 more source