Results 41 to 50 of about 226,631 (305)

The accuracy of haemoglobin A2 measurements in the presence and absence of haemoglobin S

eJHaem, 2023
The quantification of haemoglobin A2 by high‐performance liquid chromatography (HPLC) was compared with quantification by capillary electrophoresis for control subjects and patients with sickle cell trait or sickle cell anaemia.
Jane K. Myburgh, Richard M. Szydlo, Barbara J. Bain   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Multiomics integration of 16S rRNA, metagenomic, and metabolomic analyses unveils gut microbiota–metabolite interactions in Guizhi Fuling capsule‐treated chronic pelvic inflammatory disease rats

Advanced Chinese Medicine, EarlyView.
Guizhi Fuling capsule likely alleviates chronic pelvic inflammatory disease by exerting anti‐inflammatory effects, restoring TCA cycle energy metabolism, reshaping gut microbiota structure, inhibiting quorum sensing signaling, and improving polysaccharide metabolic functions.
Hongli Chen, Mengyu Qian, Zhelong Feng, Xia Gao, Ruotong Huang, Yan Xie, Liang Cao, Xialin Chen, Wei Xiao   +8 more
wiley   +1 more source

Chemical Sensors - Analytical Instruments

CHIMIA, 1999
Recent developments in our laboratory belonging to two main areas of current interest, namely amperometric gas sensors and capillary electrophoresis instrumentation, are highlighted.
Peter C. Hauser, Carlo Colombo, Alexia W.E. Hodgson, Parick Jacquinot, Thomas Kappes, Richard Stratz   +5 more
doaj   +1 more source

Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study

Metabolites, 2021
For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji   +8 more
doaj   +1 more source

Kapilarna elektroforeza u farmaciji [PDF]

, 2010
Capillary electrophoresis is a new separation technique. It is an analytical technique that usually complements or replaces high performance liquid chromatography.
Damić, Miranda, Nigović, Biljana
core   +1 more source

Strongly nonlinear waves in capillary electrophoresis

, 2012
In capillary electrophoresis, sample ions migrate along a micro-capillary filled with a background electrolyte under the influence of an applied electric field.
F. Kohlrausch, G. Whitham, I. Rubinstein, Sandip Ghosal, Zhen Chen   +4 more
core   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, EarlyView.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

Detection of Mutations in Exon 8 of TP53 by Temperature Gradient 96-Capillary Array Electrophoresis

BioTechniques, 2002
Various capillary electrophoresis applications have increasingly been utilized in mutation detection. Separation of two species is either based on secondary structure or differences in melting of DNA due to the mutation.
A. Torgunrud Kristensen, J. Bjørheim, M. Minarik, K.-E. Giercksky, P.O. Ekstrøm   +4 more
doaj   +1 more source

Engineering Hybrid Extracellular Vesicles for Functional mRNA Delivery

Advanced Functional Materials, EarlyView.
This study optimizes two methods for the generation of extracellular vesicle (EV)‐mimetic‐Lipid Nanoparticle (LNP) (CELLNPs) and EV‐LNP (HEVs) hybrid nanoparticles for messenger (mRNA) delivery. The authors screen lipid compositions to maximize hybrid nanoparticle formation and analyze the resulting nanoparticles with single particle characterization ...
Ana Filipa Louro, Inês Gomes, Chuan‐En Lu, Marco A. Alfonzo‐Méndez, Niek Dekker, Mohsin Khan, Elisa Lázaro‐Ibáñez   +6 more
wiley   +1 more source