Metabolites, 2021 For large-scale metabolomics, such as in cohort studies, normalization protocols using quality control (QC) samples have been established when using data from gas chromatography and liquid chromatography coupled to mass spectrometry.
Hiroyuki Yamamoto +8 more
doaj +1 more source
"MS-Patch-Clamp" or the Possibility of Mass Spectrometry Hybridization with Patch-Clamp Setups for Single Cell Metabolomics and Channelomics [PDF]
Advances in Biochemistry, Vol. 3, pp. 66-71 (2015), 2015 In this projecting work we propose a mass spectrometric patch-clamp equipment with the capillary performing both a local potential registration at the cell membrane and the analyte suction simultaneously. This paper provides a current literature analysis comparing the possibilities of the novel approach proposed with the known methods, such as scanning
arxiv +1 more source
Capillary zone electrophoretic studies of ion association between inorganic anions and tetraalkylammonium ions in aqueous-dioxane media [PDF]
, 2005 Ion association between inorganic anions and symmetrical tetraalkylammonium ions, R4N+ (R = Me, Et, Pr, n-Bu, n-Am, and 2-methyl butyl {isoamyl = iAm}) was investigated using ordinary silica capillary by capillary zone electrophoresis.
Akerlof +38 more
core +1 more source
The development of a method to determine felinine in body fluids by capillary electrophoresis : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Chemistry at Massey University [PDF]
, 1999 Ion-exchange, paper-chromatography and high performance liquid chromatography were used in earlier studies for the determination of felinine in biological fluids. These methods were either inadequate and/or need laborious sample pre-treatments.
Zhang, Fengying
core
Molecular Oncology, EarlyView.NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi +5 more
wiley +1 more source
Capillary electrophoresis characterisation of a rapid prototyped PMMA chip for particle analysis [PDF]
, 2010 Màster en Nanociència i NanotecnologiaA rapid and cheap method has been developed for the fabrication of a capillary electrophoresis chip for the preliminary characterization of particles.
Colom, Adai
core +1 more source
Germline variants in CDKN2A wild‐type melanoma prone families
Molecular Oncology, EarlyView.Among melanoma‐prone families, wild‐type for CDKN2A and CDK4, some have pathogenic variants in genes not usually linked to melanoma. Furthermore, rare XP‐related variants and variants in MC1R are enriched in such families. Germline pathogenic variants in CDKN2A are well established as an underlying cause of familial malignant melanoma. While pathogenic
Gjertrud T. Iversen +5 more
wiley +1 more source
New electrolyte systems for capillary zone electrophoresis of metal cations and non-ionic organic compounds [PDF]
, 1995 Capillary electrophoresis (CE) is the most attractive and very promising separation technique today due to its inherent capabilities. It is a long history from the first appearance of electrophoresis technique to modern capillary electrophoresis ...
Shi, Youchun
core +3 more sources
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Detection of Mutations in Exon 8 of TP53 by Temperature Gradient 96-Capillary Array Electrophoresis
BioTechniques, 2002 Various capillary electrophoresis applications have increasingly been utilized in mutation detection. Separation of two species is either based on secondary structure or differences in melting of DNA due to the mutation.
A. Torgunrud Kristensen +4 more
doaj +1 more source