Results 161 to 170 of about 698,895 (334)

Natural Allelic Variations in IbCHYR1–IbZnFR Complex Regulate Fusarium Root Rot Resistance in Sweet Potato

Advanced Science, EarlyView.
FfRlpA2, a conserved Fusarium effector, functions as a protease inhibitor by hijacking the E3 ubiquitin ligase IbCHYR1 to degrade the resistance factor IbZnFR, thereby promoting Fusarium pathogenicity. Conversely, the high dosage Pro::IbZnFRHap2 allele was associated with resistance to root rot disease.
Huan Zhang, Zhuoru Dai, Xiaochen Zhang, Meiqi Shang, Xiaoru Gao, Ruiqi Ma, Limeng Zhao, Xiaoli Zhang, Qingchang Liu, Hong Zhai, Shaopei Gao, Ning Zhao, Qinghe Cao, Qiang Li, Shaozhen He   +14 more
wiley   +1 more source

A Novel Synonymous Variant of PAX2 in Monochorionic Diamniotic Twins With Bilateral Renal Agenesis: A Case Report and Literature Review. [PDF]

Mol Genet Genomic Med
Yao W, Xu B, Wang H, Liu S, Wang H, Mai J, Wang X, Chen X, Zhang Z.   +8 more
europepmc   +1 more source

Designing Tunable DNA Condensates to Control Membrane Budding Transformation in Synthetic Cells

Advanced Science, EarlyView.
In giant unilamellar vesicles (GUVs), membrane wetting of encapsulated liquid‐liquid phase‐separated DNA condensates can be precisely triggered post‐fabrication using photoactivatable DNA‐lipid linkers. On free‐standing membranes, interactions between DNA condensates and the membrane lead to outward budding, resembling exocytosis.
Nastasja Kaletta, Sophia Burick, Yusuf Qudbuddin, Petra Schwille   +3 more
wiley   +1 more source

Apoptotic Bodies Restore NAD and Mitochondrial Homeostasis in Fibroblasts

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived apoptotic bodies (MSC‐ABs) target keloid fibroblasts (KFs), restoring nicotinamide adenine dinucleotide (NAD) metabolism and mitochondrial function, suppressing collagen overproduction, and rebalancing tissue homeostasis, offering a novel therapy for keloid.
Shutong Qian, Siya Dai, Chunyi Guo, Wenjun Wang, Jiajia Pang, Yichen Shen, Mingyuan Xu, Jie Hu, Wenguo Cui, Xiaoming Sun, Jinghong Xu   +10 more
wiley   +1 more source

17β-estradiol maintains extracellular matrix homeostasis of nucleus pulposus cells by activating p70 S6K1 signaling pathway. [PDF]

Front Cell Dev Biol
Liu T, Li Z, Zhang W, Guo X, Liu G, Yang D, Yang S.   +6 more
europepmc   +1 more source

Eosinophils‐Induced Lumican Secretion by Synovial Fibroblasts Alleviates Cartilage Degradation via the TGF‐β Pathway Mediated by Anxa1 Binding

Advanced Science, EarlyView.
Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen, Yuwei Zhou, Wenxiu Yuan, Yanjing Ou, Hanyu Lin, Kaixun He, Xueshen Qian, Huachen Chen, Chengchaozi Wang, Jie Lu, Weiping Chen, Dexiong Li, Jiang Chen   +12 more
wiley   +1 more source

Antimicrobial susceptibility pattern and plasmid profiles of bacterial isolates from four hospitals in Jos Metropolis

African Journal of Pharmaceutical Research and Development (AJOPRED)
Antimicrobial resistance poses a serious threat to healthcare, leading to protracted illness, increased mortality risk, and spread of infection. The World Health Organization recommends continuous surveillance of antibiotics for resistance.
Patrick Oladele Olorunfemi, Joshua Danladi Damshit, Grace Ovayoza Chris-Otubor   +2 more
doaj  

Molecular Assessment Using the MASTDISCS® Combi D72C Set for the Phenotypic Detection of Extended-Spectrum Beta-Lactamases, AmpC Beta-Lactamases, and Carbapenemase Enzymes in Escherichia coli and Klebsiella pneumoniae. [PDF]

Cureus
Haji SH, Ganjo AR, Abdulaziz SM, Abdullah ZA, Smail SB.   +4 more
europepmc   +1 more source

A Solution‐Based Deposition Method Enabling Pigment Blue Edible Electrochemical Transistors

Advanced Science, EarlyView.
A novel solution‐based method is presented to produce Copper Phthalocyanine fibrous films displaying effective ion permeability and enhanced transconductance in electrolyte‐gated transistors architectures. Using these films, the first instance of a fully edible electrolyte‐gated transistor with volumetric capacitance, targeting in‐body applications, is
Alessandro Luzio, Fabrizio M. Ferrarese, Matteo Butti, Alberto D. Scaccabarozzi, Bojan Petrović, Sanja Kojić, Goran Stojanović, Simone Fiorini Granieri, Shubham Tanwar, Adrica Kyndiah, Mario Caironi   +10 more
wiley   +1 more source

Exploring the correlation between magnetic resonance diffusion tensor imaging (DTI) parameters and aquaporin expression and biochemical composition content in degenerative intervertebral disc nucleus pulposus tissue: a clinical experimental study. [PDF]

BMC Musculoskelet Disord
Chen S, Sun S, Wang N, Fang X, Xie L, Hu F, Xi Z.   +6 more
europepmc   +1 more source