Improved Determination Method for Plasmid Copy Number Using Pulsed Field Gel Electrophoresis
Beatrix Fahnert +3 more
doaj +1 more source
A Case of <i>Vibrio vulnificus</i> Infection in a Patient with an Underlying Condition after Consuming Frozen Seafood. [PDF]
Kim DH +8 more
europepmc +1 more source
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Multi-City Outbreak of <i>Staphylococcus aureus</i> Infections Linked to Durian Mille-Feuille Cakes - Shandong Province, China, May-June 2025. [PDF]
Zhuang M +6 more
europepmc +1 more source
This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Outbreak of <i>Ralstonia pickettii</i> bacteraemia related to sterile distilled water in patients with haematological and oncological malignancies. [PDF]
Alp S +9 more
europepmc +1 more source
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source
Molecular Characterization, Virulence Profiling, and Antimicrobial Susceptibility of <i>Listeria monocytogenes</i> Isolated from Smoked Fish in Poland: A Preliminary Study. [PDF]
Strzałkowska ZJ +9 more
europepmc +1 more source
After liver transplantation, ischemia‐reperfusion injury is more severe in pericentral regions. Multiomic analyses of human grafts and mouse models identify FOXO1 activation in pericentral hepatocytes as an upstream driver of SAA secretion. SAA recruits and activates FPR2+ macrophages, amplifying local inflammation. Amilo‐5MER inhibits SAA bioactivity,
Feng Zhang +19 more
wiley +1 more source

