Results 161 to 170 of about 18,550,533 (314)

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu   +10 more
wiley   +1 more source

Solar‐Powered Electrokinetic Filtration using Hierarchical Porous Membranes for the Off‐Grid Removal of Ultrafine Contaminants

open access: yesAdvanced Science, EarlyView.
A solar‐powered nanoelectrokinetic filtration system enables high‐flux removal of ultrafine contaminants without relying on nanoscale pores or pressure‐driven membranes, offering a sustainable solution for the off‐grid water purification. Abstract The removal of ultrafine suspended solids from water remains a critical challenge due to the tradeoffs ...
Woonjae Choi   +4 more
wiley   +1 more source

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

open access: yesAdvanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang   +7 more
wiley   +1 more source

Modular programming of interaction and geometric specificity enables assembly of complex DNA origami nanostructures. [PDF]

open access: yesNat Commun
Saha R   +10 more
europepmc   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Molecular surveillance of the Plasmodium falciparum Pfmdr1 N86Y mutation linked to antimalarial drug resistance in Mbouda, Cameroon. [PDF]

open access: yesTrop Dis Travel Med Vaccines
Nadia NAC   +10 more
europepmc   +1 more source

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