Results 161 to 170 of about 510,638 (275)

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source

Common hemoglobin variants affecting the diagnosis of β-thalassemia: A large cohort data at a single center. [PDF]

PLoS One
Singha K, Srivorakun H, Yamsri S, Chaibunruang A, Pansuwan A, Changtrakul Y, Sanchisuriya K, Fucharoen G, Fucharoen S.   +8 more
europepmc   +1 more source

“Bionopoly” as a Gamechanger? Effects of Gamification on Learning Success, Motivation and Activation Among Medical Students in a Biochemistry Course

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Gamification is characterized by the use of gaming elements in a non‐gaming context. This concept is commonly applied in teaching to create a more meaningful and activating learning environment. The major aim of this study was to compare possible effects of gamification on a traditional interactive teaching concept in a biochemistry course on ...
Eva Stapfer, Ernestine Saumweber, Achim Schneider, Susanne J. Kühl   +3 more
wiley   +1 more source

Establishment of a rapid Brucella detection method based on MCDA-CRISPR dual signal amplification system for reducing transfusion-transmitted diseases. [PDF]

Sci Rep
Fu X, Zhao F, Ge J, Guan H, Lv P, Guo F, Ma H, Ainiwaer M, Hu S.   +8 more
europepmc   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

BMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen, Jianfeng Wu, Shunhan Zhang, Siqi Huang, Yingjun Xie, Hongda Chen, Yinghong Yang, Lan Xiao, Ding Wang, Keke Wu, Xiaofang Sun   +10 more
wiley   +1 more source

Dried blood spot sample extraction for metabolomics and proteomics profiling for clinical trials: a descriptive exploratory study. [PDF]

Sci Rep
Fägerstam S, Johansson E, Af Geijerstam P, Rådholm K, Ghafouri B.   +4 more
europepmc   +1 more source

Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris

Biological Diversity, EarlyView.
Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu, Jia Li, Xin Liu, Xue‐Jun Ge, Hui‐Run Huang   +4 more
wiley   +1 more source

[Retracted] Guggulsterone inhibits human cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 cell growth by inducing caspase-dependent apoptosis and downregulation of survivin and Bcl-2 expression. [PDF]

Oncol Lett
Zhong F, Yang J, Tong ZT, Chen LL, Fan LL, Wang F, Zha XL, Li J.   +7 more
europepmc   +1 more source

Paper-electrophoresis and Zone-electrophoresis of Serum Cholinesterase

YAKUGAKU ZASSHI, 1962
T, IWAMOTO, M, SAITO, K, ITO
openaire   +3 more sources

Formation and Characterization of Insoluble Anthocyanins‐λ‐carrageenan Biopolyelectrolyte Complexes: Structural Morphology, Thermal Stability, and Release Dynamics

ChemFoodChem, EarlyView.
Insoluble biopolyelectrolyte complexes formed between blackberry anthocyanins and λ‐carrageenan are investigated. Optimal complexation occurs at low carrageenan ratios and acidic pH, producing porous hydrogel‐like structures with enhanced thermal stability.
Tomás Garrido, Ana Rita Pereira, Hiléia K. S. Souza, Nuno Mateus, Victor de Freitas, Ana Fernandes   +5 more
wiley   +1 more source