Results 211 to 220 of about 510,638 (275)

Exportin 1 Inhibitor Combined With Venetoclax Induces Apoptosis in Myelodysplastic Syndrome by Mitochondria‐Induced Apoptosis Pathway

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Inhibition of XPO1 is a promising modality in the treatment of MDS, especially when combined with Venetoclax, which activates mitochondria‐mediated apoptosis and could be a potential target for MDS therapy. ABSTRACT Background Myelodysplastic syndromes (MDS) are clonal hematopoietic malignancies that pose a serious health threat.
Xiaohan Liu   +8 more
wiley   +1 more source

Exploring supported ionic liquids for IgY antibody purification

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Immunoglobulin Y (IgY), a scalable alternative to mammalian antibodies, typically found in hen's egg yolk, has gained attraction in diagnostic and therapeutic applications. However, its purification from egg yolk remains challenging due to the complex matrix and limitations of conventional techniques. Supported Ionic Liquids (SILs),
Amanda RP Silva   +4 more
wiley   +1 more source

Diagnostic modulation of subgingival proteomic biomarkers by age and smoking habits in periodontitis

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Although age and smoking influence the periodontal proteome, their impact on subgingival biomarkers for diagnosing periodontitis remains unclear. This multicenter study assessed their influence on subgingival proteins for disease detection.
Triana Blanco‐Pintos   +8 more
wiley   +1 more source

Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright   +9 more
wiley   +1 more source

Comparative analysis of microRNAs in bovine colostrum and neonatal calf blood

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND MicroRNAs (miRNAs) are short non‐coding RNAs that participate in a wide range of biological processes. MiRNAs are present in high concentrations in colostrum, and these may be potentially transferred to newborn calves being fed colostrum.
Do T Hue   +7 more
wiley   +1 more source

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