Results 241 to 250 of about 522,530 (295)

ZDHHC2‐Dependent Palmitoylation Dictates Ferroptosis and Castration Sensitivity in Prostate Cancer via Controlling ACSL4 Degradation and Lipid Peroxidation

Advanced Science, EarlyView.
Our study reveals a novel mechanism by which palmitoylation regulates ferroptosis and enzalutamide resistance in prostate cancer. Under enzalutamide resistance, the FOXA1/CXXC5/TET2 complex induces aberrant upregulation of ZDHHC2, which subsequently suppresses ferroptosis by mediating S‐palmitoylation of USP19 and degradation of ACSL4 protein in CRPC ...
Shuai Shao, Wei Li, Yulong Hong, Ruijiang Zeng, Liang Zhu, Lu Yi, Yuan Li, Yinhuai Wang, Haojie Huang, Xuewen Jiang, Xin Jin   +10 more
wiley   +1 more source

Serum Proteinogram in the Free-Living Brazilian Common Opossum (Didelphis aurita). [PDF]

Electrophoresis
Orozco AMO, Bento LD, Souto PC, Girardi FM, Castro VR, Oliveira JVG, Lopez CJR, Barros E, Campos AK, Fonseca LAD.   +9 more
europepmc   +1 more source

Population‐Based Multi‐Omics and Cohort Study Identifying Predictive Biomarkers and Therapeutic Targets for Psoriatic Disease

Advanced Science, EarlyView.
Psoriatic disease (PsD) is a chronic skin disease, with challenges in early risk stratification and drug development. Through gene‐level causal inference framework and expression level validation, combined with longitudinal cohort study, CDSN and PRSS8 have been identified as candidate biomarkers and therapeutic targets for PsD.
Tianxing Wu, Jialiang Luo, Haoyuan Qiu, Weijie Shao, Yueyang Lu, Meixuan Luo, Zhaofeng Lin, Yan Zhang, Libo Zhang, Hong Wang, Jia Zhou, Guangfeng Ruan, Peihua Cao, Daming Zuo   +13 more
wiley   +1 more source

Characterization and Valorization of the Microalgal Co-Product Spirugrass^®: Protein Profile, Iron Speciation, and Potential Use as a Supplement for Honeybees. [PDF]

Mar Drugs
Dalmonte T, Rudelli C, Alberoni D, Lembo A, Gifuni I, Andreani G, Castellari M, Isani G.   +7 more
europepmc   +1 more source

Evolutionary Divergence of an Ethylene‐Responsive Transcriptional Cascade Governs a Dose‐Dependent Balance between Cotton Fiber Length and Strength

Advanced Science, EarlyView.
A tunable, ethylene‐responsive cascade governing the dose‐dependent balance between fiber length and strength is unveiled. Elevated ethylene strengthens modern tetraploid cotton (G. hirsutum) fibers but elongates those of its diploid ancestor (G. arboreum). This phenotypic switch is traced to an evolutionary functional inversion of a conserved EIN3‐ERF‐
Jie Zhang, Mengli Yu, Yuling Guo, Jie Li, Gailing Gu, Ghulam Hussain, Shuya Ma, Fuguang Li, Hongwei Xue, Zhaoen Yang, Zuoren Yang   +10 more
wiley   +1 more source

Quantifying RNA Degradation with Single-Molecule Nanopore Sensing. [PDF]

Anal Chem
Earle MK, Alawami M, Alexii RE, Brauburger S, Keyser UF, Platnich CM.   +5 more
europepmc   +1 more source

Simple and accessible methods for quantifying isolated mucins for further evaluation. [PDF]

MethodsX
McIntire-Ray HJ, Rose ES, Krick S, Barnes JW.   +3 more
europepmc   +1 more source

Specific Aspects of SELEX Protocol: Different Approaches for ssDNA Generation. [PDF]

Methods Protoc
Garanin A, Shalaev A, Zabegina L, Kadantseva E, Sharonova T, Malek A.   +5 more
europepmc   +1 more source

Development and Application of Tetra/Penta-Nucleotide SSR Markers for Paternal Identification in the Tea Plant (<i>Camellia sinensis)</i>. [PDF]

Plants (Basel)
Liu Y, Chang K, Zhu Y, Tang D, Chen W, Tang Q, Tan L.   +6 more
europepmc   +1 more source

Synergistic effects of ultrasonication and alkaline treatment on curcumin-induced cross-linking and gelation of casein-soy protein isolate hybrids. [PDF]

Ultrason Sonochem
Wu X, Zhang M, Adhikari B, Xue F.
europepmc   +1 more source