Results 221 to 230 of about 663,442 (290)

Enrichment of Hypermethylated DNA on Chip for Cervical Cancer Detection

open access: yesAdvanced Materials Interfaces, EarlyView.
A microfluidic chip coated with surface‐immobilized methyl binding domain 2 (MBD‐2) protein receptors, is able to bind hypermethylated DNA (hmDNA) from a cancer cell line selectively. Quantification by quantitative polymerase chain reaction (qPCR) shows a 30‐fold enrichment in cervical cancer target DNA.
Ruben W. Kolkman   +7 more
wiley   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels   +7 more
wiley   +1 more source

Spider Silk–Integrated Biomimetic Micropillars With Dual Adhesion for Improved Wound Hemostasis and Healing

open access: yesAdvanced Materials Technologies, EarlyView.
The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan   +4 more
wiley   +1 more source

Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting

open access: yesAdvanced Materials Technologies, EarlyView.
A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley   +1 more source

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

open access: yesAdvanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law   +3 more
wiley   +1 more source

Toward Rapid Low‐Cost Fabrication of Single‐Nanowire Photodetectors via the Utilization of Dielectrophoresis

open access: yesAdvanced Photonics Research, EarlyView.
A scalable, low‐cost approach for assembling single germanium nanowires (NWs) into photodetectors is demonstrated using a modified dielectrophoresis method with a voltage‐divider circuit. This self‐limiting assembly technique achieves ultrahigh responsivity (>6 × 105 A W−1) at 700 and 1550 nm without requiring nanoscale electrodes, offering a versatile
Siriny Laumier   +3 more
wiley   +1 more source

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