Results 241 to 250 of about 663,442 (290)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

open access: yesAdvanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong   +16 more
wiley   +1 more source

Pre‐Administration of Akkermansia Muciniphila Prevents the Development of Severe Acute Graft‐Versus‐Host Disease in Systemic Organs

open access: yesAdvanced Science, EarlyView.
Akkermansia muciniphila, a next‐generation probiotic, alleviates acute graft‐versus‐host disease (aGvHD) following allogeneic hematopoietic stem cell transplantation (HSCT) by providing protective effects across multiple organs. Pre‐colonization with A.
Jeong‐Eun Han   +9 more
wiley   +1 more source
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Capillary Electrophoresis

Science, 1988
Electrophoretic separations carried out in capillary tubes offer the possibilities of rapid and automated analyses of small volumes of complex mixtures with unprecedented resolution and sensitivity. Some emerging developments of this new instrumentation are reviewed.
M J, Gordon   +3 more
openaire   +3 more sources

Capillary electrophoresis

Talanta, 1994
The most important characteristics of capillary electrophoresis are studied. Principles of the technique, instrumentation employed and the most important applications are described.
M L, Marina, M, Torre
openaire   +2 more sources

Displacement electrophoresis

Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences, 1967
The method of displacement electrophoresis is described and its analogy with displacement chromatography shown. The apparatus consists basically of a capillary tube, a few tenths of a millimetre bore and thin walled, uniting two vessels, each containing an electrode.
Martin, A.J.P., Everaerts, F.M.
openaire   +2 more sources

Cationic Electrophoresis

2012
Denaturing, discontinuous electrophoresis in the presence of SDS has become a standard method for the protein scientist. However, there are situations where this method produces suboptimal results. In these cases, electrophoresis in the presence of positively charged detergents such as cetyltrimethylammonium bromide (CTAB) may work considerably better.
openaire   +3 more sources

Capillary electrophoresis

Current Opinion in Biotechnology, 1992
The past year has seen major advances in capillary electrophoresis in terms of broadening applicability. A variety of successful approaches to peptide/protein and DNA separation and analysis are now available, and techniques for saccharide analysis are developing rapidly.
openaire   +2 more sources

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