Results 141 to 150 of about 1,070,231 (293)

Increased excitability of layer 5 neocortical pyramidal neurons and its contribution to seizure activity in Gabrg2 gene-deficient mice

iScience
Summary: Gabrg2fl/wtCre+ (CKO) mice are one of the models for studying “genetic epilepsy with febrile seizures plus (GEFS+).” A previous study revealed increased cortical excitability in CKO mice subjected to hyperthermia (CKO-heat mice), but the ...
Yangyang Sun, Zhuoqi Li, Baocong Yu, Chun Zhang, Lei Wang, Baorui Guo, Jiangwei Ding, Lifei Xiao, Peng Gao, Xinxiao Li, Tao Sun   +10 more
doaj   +1 more source

Electron compensation‐gated nanomotor for immunomodulation and microenvironment remodeling in bacterial pneumonia therapy

BMEMat, EarlyView.
A nanomotor featuring an “electronic lock” via electron compensation in an Au‐Ag alloy ensures therapeutic precision. Near‐infrared light acts as a key, unlocking on‐demand Ag+ release for synergistic bactericidal action and microenvironment remodeling to potently treat bacterial pneumonia. Abstract Bacterial pneumonia treatment is severely hampered by
Chenglong Xue, Xiaoyu Zhao, Yuqian Wang, Lijin Shi, Qi Shuai   +4 more
wiley   +1 more source

Graciloplasty, electrostimulation, electromyography. Clinical implications of electrophysiological phenomena in the neo-sphincter created from the gracilis muscle.

Polski przeglad chirurgiczny, 2016
The aim of the study was to compare the electrophysiological phenomena occurring in the gracilis muscle, transposed into the pelvic floor during the graciloplasty procedure, subjected to continuous electrical stimulation by means of implanted stimulator, or regular stimulation by means of an external device, as well as the long-term functional results ...
Romaniszyn, Michał, Wałęga, Piotr
openaire   +4 more sources

Electrophysiological identification of nerves of the larynx among the tissuesof operative wound in goiter surgeries [PDF]

, 2017
The objective of the study was to analyze the technology of electrophysiological identification of laryngeal nerves in goîter surgeries. Methods: The technology of electrophysiological identification of laryngeal nerves in goiter surgeries was developed.
Kristina A. Chympoi, Oleksandr V. Shidlovskyi, Nina P. Tkachuk, Volodymyr V. Bezruk, Marina D. Gresko, Viktor O. Shidlovskyi, Victor M. Batig, Michael I. Sheremet, Tetyana O. Bezruk, Anatoly D. Bedenyuk, Vitaliy V. Maksymyuk   +10 more
core  

Electrophysiological study of the violence inhibition mechanism in relation to callous-unemotional and aggressive traits

, 2017
The violence inhibitionmechanism (VIM) proposes that observing another’s distress inhibits responses that can lead to violent behaviour. Dysfunction of this system is associated with disorders characterised by aggressive and callous-unemotional traits ...
Miguel G.E. Santo, Sumich, Alexander L., Alexander L. Sumich, Gregson, M, Claire A.J. Bloxsom, Gregson, Michael, Bloxsom, Claire A.J., Santo, M, Bloxsom, C, Fido, D, Santo, Miguel G.E., Fido, Dean, Michael Gregson, Sumich, A, Dean Fido   +14 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Localizing value of cutaneous ictal phenomena: A systematic review

Epileptic Disorders, EarlyView.
Abstract Objective Clinical observation of autonomic signs during seizures can aid in localizing the epileptogenic zone (EZ). We performed a systematic review and meta‐analysis to evaluate the localizing value of ictal cutaneous phenomena—piloerection, sweating, pallor, and flushing—in focal epilepsy and their relevance to presurgical evaluation ...
R. Rocamora, L. Vilella, L. Panadés‐De Oliveira, F. Álvarez‐Gómez, T. Ibáñez, A. Celdrán, G. Zimmermann, R. Zucca   +7 more
wiley   +1 more source

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

Epileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu, Agnès Trébuchon, Fabrice Bartolomei   +2 more
wiley   +1 more source

Extracellular ATP in the lymphohematopoietic system: P2Z purinoceptors and membrane permeabilization

Brazilian Journal of Medical and Biological Research, 1998
The effects of extracellular nucleosides and nucleotides on many organs and systems have been recognized for almost 50 years. The effects of extracellular ATP (ATPo), UTPo, ADPo, and other agonists are mediated by P2 purinoceptors.
Persechini P.M., Bisaggio R.C., Alves-Neto J.L., Coutinho-Silva R.   +3 more
doaj  

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

Epileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron, Laure Salmon, Nicolas Nguyen, Dènahin Toffa, Sami Obaid, Alexis Robin, Dang Khoa Nguyen   +6 more
wiley   +1 more source