Results 161 to 170 of about 1,070,231 (293)

Metabolic mimicry of perioral myoclonia with absences: A signature of thalamocortical instability in childhood‐onset ornithine transcarbamylase deficiency

Epileptic Disorders, EarlyView.
José Augusto Bragatti, Letícia Grigoletto   +1 more
wiley   +1 more source

Classifying seizures in practice: Testing the 2025 ILAE framework among clinicians in South Africa

Epilepsia, EarlyView.
Abstract Objective The 2025 International League Against Epilepsy (ILAE) seizure classification introduced a basic version for nonspecialists, but its usability is untested. We evaluated whether a multidisciplinary frontline workforce in South Africa could apply it, how consistently, and whether performance improved after self‐directed exposure ...
Aayesha J. Soni, Sarah Jacobs, Muhammad Ilyaas Amien, Abdullah J. Soni, Faeeza Cassim, Sa'ad Lahri, Naeem Brey, Misha Janse van Rensburg, Avumile Nongogo Futwa, Johnre Els, Keashe Adams, Bilal Irfan, M. Claudia Burbano, Jorge G. Burneo   +13 more
wiley   +1 more source

From Neurovascular Compression to Neural Hyperexcitability: Integrating Microanatomy, Electrophysiology, and Computational Neuroscience to Understand Trigeminal Neuralgia and Hemifacial Spasm. [PDF]

Cells
Okuhata H, Aihara M, Oya S, Nagai R, Aizawa K.   +4 more
europepmc   +1 more source

Theta oscillations, epileptogenesis, and focal seizures in rodent models of mesial temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Theta oscillations (4–12 Hz) are a prominent network rhythm within hippocampal and parahippocampal structures. Driven by cholinergic and γ‐aminobutyric acidergic inputs originating from the medial septum, physiological theta gates network excitability to control spatial navigation, memory encoding, and sensorimotor integration during specific ...
Maxime Lévesque, Massimo Avoli
wiley   +1 more source

Beyond Biomarkers: Reclaiming the Central Role of Clinical Neurophysiology in Neuromuscular Disorders. [PDF]

Brain Sci
Mangiardi M.
europepmc   +1 more source

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

Epilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Modeling Negative Symptom Domain Neurobiology: Protocol for an Observational, Transdiagnostic, Translational Study. [PDF]

JMIR Res Protoc
Oprea DC, Untu I, Vieru DS, Dascălu C, Speyer H, Dobre C, Green O, Dobrin RP, Davidson M, Rabinowitz J, Tamba BI.   +10 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

A case of low-frequency myokymia visualized by simultaneous EMG-ultrasound recording. [PDF]

Clin Neurophysiol Pract
Sugimoto T, Naito H, Tachiyama K, Yokosaki M, Hironaka A, Nakamori M, Yamazaki Y, Kurokawa K, Maruyama H.   +8 more
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source