Results 91 to 100 of about 269,022 (329)

Arrhythmias After Tetralogy of Fallot Repair [PDF]

, 2005
Tetralogy of Fallot is the most common cyanotic congenital heart disease, with a good outcome after total surgical correction. In spite of a low perioperative mortality and a good quality of life, late sudden death remains a significant clinical problem,
Daliento, Luciano, Folino, Antonio Franco   +1 more
core   +1 more source

Delta Opioid Receptors within the Cortico‐Thalamic Circuitry Underlie Hyperactivity Induced by High‐Dose Morphine

Advanced Science, EarlyView.
Morphine activates the excitatory cingulate cortex–intermediate rostrocaudal division of zona incerta (Cg‐ZIm) pathway to drive hyperlocomotion in mice. Inhibiting the Cg‐ZIm pathway attenuates both acute and chronic morphine‐induced hyperlocomotion, while its activation mimics morphine's motor effects.
Chun‐Yue Li, Huiqian Huang, Xiao‐Fan Shen, Ke‐Lei Cao, Di Zheng, Yi Zhu, Shi‐Ze Xie, Xiao‐Dan Yu, Hao Wang, Jia‐Dong Chen, Jie Shi, Yue Li, Min Yan, Xiao‐Ming Li   +13 more
wiley   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Multi-fidelity classification using Gaussian processes: accelerating the prediction of large-scale computational models

, 2019
Machine learning techniques typically rely on large datasets to create accurate classifiers. However, there are situations when data is scarce and expensive to acquire.
Costabal, Francisco Sahli, Hurtado, Daniel E., Kuhl, Ellen, Perdikaris, Paris   +3 more
core   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

In vitro Effects of Two Silver Electrodes on Select Wound Pathogens [PDF]

, 1995
The use of electrical current to promote wound healing is well documented. However, little is understood about the effects of micro-amperage direct current (μADC) on growth of wound pathogens.
Kloth, Luther C., Laatsch-Lybeck, Linda Jean, Ong, Poh Chye   +2 more
core   +1 more source

Electrophysiology of living organs from first principles [PDF]

, 2010
Günter Scharf, Christoph Scharf
openalex   +1 more source

A neural probe for concurrent real-time measurement of multiple neurochemicals with electrophysiology in multiple brain regions in vivo

, 2023
Uikyu Chae, Jiwan Woo, Yakdol Cho, Jeong-Kyu Han, Soo Hyun Yang, Esther Yang, Hyogeun Shin, Hyun Kim, Hyun‐Yong Yu, C. Justin Lee, Il‐Joo Cho   +10 more
openalex   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

Advanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Delta-wave automatic mapping of the manifest accessory pathway

Frontiers in Cardiovascular Medicine
BackgroundDespite the high success rate of radiofrequency catheter ablation (RFCA) in Wolff-Parkinson-White Syndrome (WPW), localizing the successful ablation site can be challenging and may require multiple radiofrequency (RF) applications.ObjectiveThis
Saverio Iacopino, Gennaro Fabiano, Paolo Sorrenti, Andrea Petretta, Jacopo Colella, Alessandro Di Vilio, Giovanni Statuto, Nicolangelo Diomede, Paolo Artale, Pasquale Filannino, Pasquale Filannino, Antonino Pardeo, Filippo Placentino, Giuseppe Campagna, Gianluca Peluso, Edoardo Cecchini, Federico Cecchini, Giuseppe Speziale, Giuseppe Speziale, Fiorenzo Gaita   +19 more
doaj   +1 more source