Results 181 to 190 of about 258,626 (258)

Causal AI in Cardiac Arrhythmia: From Pattern Recognition to Mechanistic Insight. [PDF]

Clin Cardiol
AbuBaha B, Aldwaik S, Saife S, Mahmoud-Barqawi Y, Omar L, Sawafta O, Sawalha M, Nassar H, Alqasem Z, Khuffash K, Salameh H, AbuBaha M.   +11 more
europepmc   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Left bundle branch area pacing: For all and by all! No longer the exclusive domain of the electrophysiologist! [PDF]

Indian Pacing Electrophysiol J
Ghosh A, Pandurangi UM.
europepmc   +1 more source

The Dynamics of Neurofilament Light Chain in Spinal Muscular Atrophy

Annals of Neurology, EarlyView.
Objective Newborn screening (NBS) for spinal muscular atrophy (SMA) facilitates early diagnosis and treatment for affected individuals. However, fluid biomarkers that provide early insights into disease activity and outcomes in a neonatal cohort and those unable to access (due to reimbursement criteria) or deferring immediate treatment are lacking ...
Arlene D'Silva, Karen Herbert, Lakshmi Balaji, Jia Mei He, Tejaswi Kandula, Hugo A. Sampaio, Hooi‐Ling Teoh, Esther Tantsis, Jihee Sohn, Nancy Briggs, Nickson Ning, Matthew C. Kiernan, Didu S. Kariyawasam, Michelle A. Farrar   +13 more
wiley   +1 more source

Electroanatomic mapping of atrial tachycardia—Manual vs automated annotation

HeartRhythm Case Reports, 2017
Sven Knecht, ScD, Florian Spies, MSc, David Altmann, MD, Tobias Reichlin, MD, Christian Sticherling, MD, Michael Kühne, MD   +5 more
doaj   +1 more source

Rapid calibration of atrial electrophysiology models using Gaussian process emulators in the ensemble Kalman filter. [PDF]

Sci Rep
Mamajiwala M, Corrado C, Lanyon CW, Niederer SA, Wilkinson RD, Clayton RH.   +5 more
europepmc   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution

Angewandte Chemie International Edition, EarlyView.
Novel and biocompatible photoactivatable oxytocin and vasopressin probes, utilising state‐of‐the‐art photocages, remain inactive in the dark. Light exposure facilitates rapid spatiotemporal receptor activation and phospholipase C (PLC)‐mediated downstream signalling. Figure created in https://BioRender.com.
Konstantin Raabe, Predrag Kalaba, Xuan Ling Hilary Yong, Greta Crudeli, Sarah Melzer, Erik Keimpema, Victor Anggono, Markus Muttenthaler   +7 more
wiley   +1 more source

Response to 'promising advances and remaining challenges in AI-driven QTc estimation' by Zekai Yu. [PDF]

Europace
Plagwitz L, Doldi F, Magerfleisch J, Zotov M, Bickmann L, Heider D, Varghese J, Eckardt L, Büscher A.   +8 more
europepmc   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

Arthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel, Manigandan Venkatesan, Rahul S. Jasrotia, Yuyang Sun, Viviane Nascimento Da Conceicao, Neelanjan Vishnu, Shankara N Varadarajan, Venugopal R. Bovilla, Rajender K Motiani, Shobhan Gaddameedhi, Bibhuti B. Mishra, Muniswamy Madesh, Brij B. Singh   +12 more
wiley   +1 more source

Rethinking small vessel CTOs: collateral channels as a bridge to subsequent complex intervention-a case report. [PDF]

Eur Heart J Case Rep
Su Z, Li J, Yuan W, Wang J, Lin M.
europepmc   +1 more source