Results 191 to 200 of about 202,862 (302)

Combined unipolar and bipolar voltage mapping for atrial substrate assessment: associations with arrhythmia recurrence after redo ablation. [PDF]

Europace
Mohsen Y, Ali SY, Sabareesan S, Sakata K, Knitter M, Hain J, Horlitz H, Steffens L, Antoun I, Horlitz M, Stöckigt F, Trayanova N.   +11 more
europepmc   +1 more source

From operating room to circuit mechanisms: Clinical basic science partnerships as a strategic model for human neuroscience

Epilepsia, EarlyView.
Abstract Epilepsy surgery offers a unique opportunity to connect clinical care with fundamental research on the human brain. Tissue resected as part of indicated surgical treatment can be studied using electrophysiology, imaging, transcriptomics, proteomics, connectomics, and computational modeling without altering the clinical procedure or exposing ...
Karl Roessler
wiley   +1 more source

Letter from the Editor in Chief. [PDF]

J Innov Card Rhythm Manag
Nair D.
europepmc   +1 more source

Scn1a‐mediated developmental regulation of prefrontal cortex plasticity and cognition

Epilepsia, EarlyView.
Abstract Objective The voltage‐gated sodium channel Nav1.1, encoded by Scn1a, is essential for γ‐aminobutyric acid (GABA)ergic function, and its alteration is associated with neurological disorders such as Dravet syndrome and Alzheimer's disease. We previously demonstrated that local Nav1.1 dysfunction in the medial prefrontal cortex (mPFC) during ...
Maurizio S. Riga, Mercedes Pérez‐Fernández, Yuniesky Andrade‐Talavera, Benito Domínguez‐Velasco, Antonio Rodríguez‐Moreno, Manuel Álvarez‐Dolado   +5 more
wiley   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free-Moving Mice. [PDF]

Adv Healthc Mater
Wu B, Thompson C, Deakin T, Xu Y, McClung CA, Cui XT.   +5 more
europepmc   +1 more source

Kv3.1 activation suppresses provoked and spontaneous seizures in a mouse Dravet syndrome model

Epilepsia, EarlyView.
Abstract Objective γ‐Aminobutyric acidergic (GABAergic) parvalbumin‐positive (PV+) interneurons are critical for maintaining cortical inhibitory tone, with their dysfunction predictably leading to epilepsy. Rapid PV+ interneuron firing is essential for their normal function and is maintained in part by potassium voltage‐gated channels.
Sheryl Anne D. Vermudez, Mustafa Q. Hameed, Yongho Choe, Gabrielle E. McGinty, Amanda M. Liebhardt, Rui Lin, Benjamin Hui, Yini Liang, David J. Arce, Henry H. C. Lee, Mustafa Sahin, Alexander Rotenberg   +11 more
wiley   +1 more source

Exercise-Provoked Wide-Complex Tachycardia and Extreme Duke Score: Orthodromic Reciprocating Tachycardia Unmasked by Electrophysiology Study. [PDF]

JACC Case Rep
Ray N, Petty A, Money D, Bracewell N.
europepmc   +1 more source

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

Epilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi, Simone Brusco, Serena Gea Giannelli, Vania Broccoli, Gaia Colasante   +4 more
wiley   +1 more source

Alternating bundle branch block and infra-Hisian Mobitz II block: an educational case of rapidly progressive His-Purkinje disease. [PDF]

Eur Heart J Case Rep
Hernandez S, Isber R, Bhanushali K, Fahed J, Isber N.   +4 more
europepmc   +1 more source

Repetitive clustered low‐voltage fast activity on intracranial electroencephalogram in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy: A candidate electroencephalographic biomarker study

Epilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE) is a recently recognized cause of drug‐resistant focal epilepsy. It is often magnetic resonance imaging‐negative or radiologically resembles focal cortical dysplasias, which makes recognition difficult and limits presurgical counseling ...
Vadym Gnatkovsky, Ekaterina Poguzhelskaya, Valeri Borger, Tobias Baumgartner, Rainer Surges, Kerstin Alexandra Klotz, Valentina Zschernack, Till Hartlieb, Manfred Kudernatsch, Ahmed Gaballa, Thomas Cloppenborg, Friedrich G. Woermann, Thilo Kalbhenn, Hajo Hamer, Stephanie Gollwitzer, Stefan Rampp, Daniel Delev, Florian Mayer, Karl Rössler, Valerie Anne Quinot, Angelika Mühlebner, Rafael Toledano, Antonio Gil‐Nagel, Roland Coras, Ingmar Blümcke, Katja Kobow   +25 more
wiley   +1 more source