Results 31 to 40 of about 198,491 (299)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Long‐Term Impact of Right Ventricular Pacing on Left Ventricular Systolic Function in Pacemaker Recipients With Preserved Ejection Fraction: Results From a Large Single‐Center Registry

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundThere is limited evidence of long‐term impact of right ventricular pacing on left ventricular (LV) systolic function in pacemaker recipients with preserved LV ejection fraction (LVEF).
Micaela Ebert   +9 more
doaj   +1 more source

The year in electrophysiology

open access: yesJournal of the American College of Cardiology, 2004
The advances in cardiac electrophysiology during 2003 will be divided into three basic categories: mechanisms , genetics , and therapy , the latter including ablation, devices, drugs, and a unique pacing application in heart failure.
openaire   +2 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

open access: yesAdvanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou   +6 more
wiley   +1 more source

Electrophysiology lab efficiency using cryoballoon for pulmonary vein isolation in Latin America: A sub-analysis of the Cryo Global Registry Study

open access: yesMedwave
Objective Cryoballoon ablation for pulmonary vein isolation is a time-efficient procedure that can alleviate stress on electrophysiology lab resources. This analysis modeled the impact of cryoballoon ablation on electrophysiology lab operation using data
Armando Pérez-Silva   +10 more
doaj   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz   +9 more
wiley   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

open access: yesAdvanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi   +10 more
wiley   +1 more source

Atrial fibrillation: A review of modifiable risk factors and preventive strategies

open access: yesRomanian Journal of Internal Medicine, 2019
Atrial fibrillation (AF), as the most common cardiac arrhythmia worldwide, is associated with increased mortality and morbidity. Successful therapeutic strategies have been introduced so far, but they are associated with significant costs.
Shamloo Alireza Sepehri   +3 more
doaj   +1 more source

Bradycardia in Patients with Subcutaneous Implantable Defibrillators—An Overestimated Problem? Experience from a Large Tertiary Centre and a Review of the Literature

open access: yesReviews in Cardiovascular Medicine, 2022
Background: The subcutaneous ICD (S-ICD) has developed as a valuable alternative to transvenous implantable cardioverter defibrillator (ICD) systems. However there are certain peculiarities which are immanent to the S-ICD and may limit its use.
Kevin Willy   +11 more
doaj   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto   +10 more
wiley   +1 more source

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