Results 41 to 50 of about 198,491 (299)

Tripolar versus bipolar ablation: insights into lesion growth and geometry using a novel ablation approach for therapy-refractory ventricular arrhythmias

Scientific Reports
Efficacy of bipolar radiofrequency ablation (BA) is often limited by high impedance between the two ablation catheters in cases of therapy-refractory ventricular tachycardias.
Fabian Bahlke, Edison Abdiu, Emily Schultz, Nico Erhard, Florian Englert, Alexander Duda, Hannah Krafft, Miruna Popa, Jan Syväri, Madeleine Tydecks, Alex Tunsch Martinez, Theresa Reiter, Marta Telishevska, Eva Koops, Sarah Lengauer, Gabriele Hessling, Isabel Deisenhofer, Raphael Spittler   +17 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free‐Moving Mice

Advanced Healthcare Materials, EarlyView.
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu, Cort Thompson, Thomas Deakin, Yan Xu, Colleen A. McClung, Xinyan Tracy Cui   +5 more
wiley   +1 more source

Shaped Apertures in Photoresist Films Enhance the Lifetime and Mechanical Stability of Suspended Lipid Bilayers [PDF]

, 2014
Planar lipid bilayers suspended in apertures provide a controlled environment for ion channel studies. However, short lifetimes and poor mechanical stability of suspended bilayers limit the experimental throughput of bilayer electrophysiology experiments.
Kalsi, S., Powl, A.M., Wallace, Bonnie A., Wallace, B.A., Morgan, Hywel, Kalsi, Sumit, Morgan, H., de Planque, M.R.R., Powl, Andrew M., de Planque, Maurits R.R.   +9 more
core   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Very high power short duration as re-ablation strategy for recurrent atrial fibrillation

BMC Cardiovascular Disorders
Background After initially successful pulmonary vein isolation (PVI), some patients experience recurrence of AF requiring repeat catheter ablation. Radiofrequency ablation (RFA) is then mostly performed with low power long duration settings (LPLD), while
Jana Ackmann, Jonas Wörmann, Jakob Lüker, Jan-Hendrik Schipper, Jan-Hendrik van den Bruck, Cornelia Scheurlen, Sebastian Dittrich, Friederike Pavel, Theodoros Maximidou, Daniel Steven, Arian Sultan   +10 more
doaj   +1 more source

Conformal Thermoreversible Gelatin‐Based Gel for High‐Fidelity Electrophysiological Recording and Acute Peripheral Nerve Interfacing

Advanced Materials, EarlyView.
A thermoreversible gelatin‐based gel forms a soft, conformal bioelectronic interface on complex biological surfaces. The flowable precursor penetrates hair‐dense regions, solidifies in situ, and maintains low impedance through adaptive contact and hydration retention.
Ruinan Hao, Yong Yuan, Jie Gao, Tong Wang, Jinzhi Du, Feng Tian, Xiaoli Li, Ruirui Qiao, Liqun Zhang, Jiajia Xue   +9 more
wiley   +1 more source

Conformable Ferrimagnetic Tattoo Electrodes for Plant Electrophysiology

Advanced Materials Technologies, EarlyView.
The newly developed ferrimagnetic tattoo electrode is capable of measuring plant electrophysiological activity outside the Faraday cage. Its ability to adhere without damaging the plant tissue allows long‐term recordings. This premise opens new avenues for in‐field monitoring of plant health through electrophysiology.
Arianna Melis, Andrea Spanu, Fabrizio Antonio Viola, Abdul Manan Dar, Alexandra Sandéhn, Cyril Routier, Annalisa Bonfiglio, Eleni Stavrinidou   +7 more
wiley   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source