Results 11 to 20 of about 9,796 (284)

Neurosteroids and Seizure Activity

open access: yesFrontiers in Endocrinology, 2020
Still circa 25% to 30% of patients with epilepsy cannot be efficiently controlled with available antiepileptic drugs so newer pharmacological treatment options have been continuously searched for.
Barbara Miziak   +2 more
doaj   +1 more source

An experimental evaluation of anticonvulsant activity of aqueous extract of Caralluma dalzielii N.E. Brown

open access: yesPhytomedicine Plus, 2023
Ethnopharmacological Relevance: Caralluma dalzielii belongs to the family of Asclepiadiaceae. It is a succulent perennial plant widely distributed across the Sahel region from Senegal to Northwest Nigeria.
Chinenye J. Ugwah-Oguejiofor   +5 more
doaj   +1 more source

Searching for New Leads to Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents [PDF]

open access: yes, 2018
The purpose of this investigation is to contribute to the development of new anticonvulsant drugs to treat patients with refractory epilepsy. We applied a virtual screening protocol that involved the search into molecular databases of new compounds and ...
Bruno Blanch, Luis Enrique   +8 more
core   +2 more sources

Using Deep Learning algorithms to detect the success or failure of the Electroconvulsive Therapy (ECT) sessions

open access: yesProceedings of the International Florida Artificial Intelligence Research Society Conference, 2021
Major Depression Disorder (MDD) is a big problem in our society. MDD can cause suicide and take families apart. When treatment with medications fail, mental healthcare professionals, use Electroconvulsive Therapy (ECT) to treat patients with MDD.
usef faghihi, Cyrus kalantarpour
doaj   +1 more source

Evaluation of Anticonvulsant Activity of 80% Methanolic Root Bark Extract and Solvent Fractions of Pentas schimperiana (A. Rich.) Vatke (Rubiaceae) in Swiss Albino Mice

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, 2021
Background. Epilepsy is one of the most common serious neurological disorders, responsible for substantial morbidity and mortality due to limited efficacy and negative properties of antiepileptic drugs.
Nebeyi Fisseha   +2 more
doaj   +1 more source

Physical, chemical and sensory evaluation of meat from cobia (rachycentron canadum), desensitized with different voltages of electric shock, stored under refrigeration

open access: yesCiência Rural, 2019
: Fish quality is conditioned by several factors, among them desensitization methods applied for fish managing and slaughtering. This research used electric shock at different intensities as a desensitization method for cobia (Rachycentron canadum ...
Fúlvio Viegas Santos Teixeira de Melo   +5 more
doaj   +1 more source

Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models. [PDF]

open access: yesPLoS ONE, 2016
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases.
Wolfgang Fischer   +8 more
doaj   +1 more source

Electroshock treatment dependent microstructural evolution and mechanical properties of near-β titanium alloy manufactured by directed energy deposition

open access: yesMaterials & Design, 2021
Effects of electroshock treatment (EST) on the microstructural evolution and mechanical properties of near-β titanium alloy (Ti-55531) formed by directed energy deposition (DED) was studied in this work.
Haojie Guo   +8 more
doaj   +1 more source

The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs [PDF]

open access: yes, 2019
Up to date, preclinical screening for new antiepileptic substances is performed by a combination of different in vivo models of acute seizures, for which large numbers of animals are necessary.
Dag, Ramazan   +4 more
core   +1 more source

Looming struggles over technology for border control [PDF]

open access: yes, 2006
New technologies under development, capable of inflicting pain on masses of people, could be used for border control against asylum seekers. Implementation might be rationalized by the threat of mass migration due to climate change, nuclear disaster or ...
Brian Martin   +12 more
core   +1 more source

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