Results 11 to 20 of about 9,796 (284)
Neurosteroids and Seizure Activity
Still circa 25% to 30% of patients with epilepsy cannot be efficiently controlled with available antiepileptic drugs so newer pharmacological treatment options have been continuously searched for.
Barbara Miziak +2 more
doaj +1 more source
Ethnopharmacological Relevance: Caralluma dalzielii belongs to the family of Asclepiadiaceae. It is a succulent perennial plant widely distributed across the Sahel region from Senegal to Northwest Nigeria.
Chinenye J. Ugwah-Oguejiofor +5 more
doaj +1 more source
Searching for New Leads to Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents [PDF]
The purpose of this investigation is to contribute to the development of new anticonvulsant drugs to treat patients with refractory epilepsy. We applied a virtual screening protocol that involved the search into molecular databases of new compounds and ...
Bruno Blanch, Luis Enrique +8 more
core +2 more sources
Major Depression Disorder (MDD) is a big problem in our society. MDD can cause suicide and take families apart. When treatment with medications fail, mental healthcare professionals, use Electroconvulsive Therapy (ECT) to treat patients with MDD.
usef faghihi, Cyrus kalantarpour
doaj +1 more source
Background. Epilepsy is one of the most common serious neurological disorders, responsible for substantial morbidity and mortality due to limited efficacy and negative properties of antiepileptic drugs.
Nebeyi Fisseha +2 more
doaj +1 more source
: Fish quality is conditioned by several factors, among them desensitization methods applied for fish managing and slaughtering. This research used electric shock at different intensities as a desensitization method for cobia (Rachycentron canadum ...
Fúlvio Viegas Santos Teixeira de Melo +5 more
doaj +1 more source
Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models. [PDF]
The ATP-gated P2X7 receptor (P2X7R) is a non-selective cation channel which senses high extracellular ATP concentrations and has been suggested as a target for the treatment of neuroinflammation and neurodegenerative diseases.
Wolfgang Fischer +8 more
doaj +1 more source
Effects of electroshock treatment (EST) on the microstructural evolution and mechanical properties of near-β titanium alloy (Ti-55531) formed by directed energy deposition (DED) was studied in this work.
Haojie Guo +8 more
doaj +1 more source
The 4-Aminopyridine Model of Acute Seizures in vitro Elucidates Efficacy of New Antiepileptic Drugs [PDF]
Up to date, preclinical screening for new antiepileptic substances is performed by a combination of different in vivo models of acute seizures, for which large numbers of animals are necessary.
Dag, Ramazan +4 more
core +1 more source
Looming struggles over technology for border control [PDF]
New technologies under development, capable of inflicting pain on masses of people, could be used for border control against asylum seekers. Implementation might be rationalized by the threat of mass migration due to climate change, nuclear disaster or ...
Brian Martin +12 more
core +1 more source

