Results 91 to 100 of about 299,485 (282)

Human myocardial protein pattern reveals cardiac diseases [PDF]

open access: yes, 2012
Proteomic profiles of myocardial tissue in two different etiologies of heart failure were investigated using high performance liquid chromatography (HPLC)/Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS).
Baykut, Doan   +5 more
core   +2 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

Artificial Cilia for 360° Direction‐Sensitive Acoustic Sensing Through Additive Micromanufacturing

open access: yesAdvanced Electronic Materials
Directional acoustic sensing can be used for localization and detection, has a wide range of applications in various fields, including rescue robotics, drone positioning, and underwater navigation.
Yikang Li   +14 more
doaj   +1 more source

Experimental Analysis of Electrohydrodynamic Jet Actuation Modes Based on the Phase Doppler Technique

open access: yesActuators
Electrosprays have garnered significant interest across various fields, from automotive painting to aerospace propulsion, due to their versatility and precision.
Gustavo Nunes   +3 more
doaj   +1 more source

Time-resolved universal temperature measurements using NaYF4:Er3+,Yb3+ upconverting nanoparticles in an electrospray jet

open access: yesBeilstein Journal of Nanotechnology, 2018
Hexagonal upconverting nanoparticles (UCNPs) of NaYF4:Er3+,Yb3+ (ca. 300 nm) have been widely used to measure the temperature at the nanoscale using luminescence ratio thermometry. However, several factors limit their applications.
Kristina Shrestha   +3 more
doaj   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

open access: yesAdvanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li   +5 more
wiley   +1 more source

FALSE SUGAR SEQUENCE PHENOMENON AND STRUCTURAL ANALYSIS OF α-HEDERIN AND HEDERACOSIDE C THROUGH ELECTROSPRAY IONIZATION AND MULTI-STAGE TANDEM MASS SPECTROMETRY

open access: yesVitae, 2011
Saponins are glycosides regularly found in plants, and they are frequently analyzed by means of electrospray ion sources and tandem mass spectrometry (ESI/MSn), not only to obtain an overall molecular weight through the high sensitivity of mass ...
Guillermo MONTOYA, Nora JIMÉNEZ
doaj  

Exploring the Phytochemical Landscape of the Early-Diverging Flowering Plant Amborella trichopoda Baill. [PDF]

open access: yes, 2019
Although the evolutionary significance of the early-diverging flowering plant Amborella (Amborella trichopoda Baill.) is widely recognized, its metabolic landscape, particularly specialized metabolites, is currently underexplored.
Chang, Lijing   +3 more
core   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen   +16 more
wiley   +1 more source

Chromatographic, Spectrometric and NMR Characterization of a New Set of Glucuronic Acid Esters Synthesized by Lipase [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2007
An enzymatic synthesis was developed on a new set of D-glucuronic acid esters and particularly the tetradecyl-D-glucopyranosiduronate also named tetradecyl D-glucuronate.
Michel Marlier   +8 more
doaj  

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