Results 71 to 80 of about 209,623 (240)

FALSE SUGAR SEQUENCE PHENOMENON AND STRUCTURAL ANALYSIS OF α-HEDERIN AND HEDERACOSIDE C THROUGH ELECTROSPRAY IONIZATION AND MULTI-STAGE TANDEM MASS SPECTROMETRY

Vitae, 2011
Saponins are glycosides regularly found in plants, and they are frequently analyzed by means of electrospray ion sources and tandem mass spectrometry (ESI/MSn), not only to obtain an overall molecular weight through the high sensitivity of mass ...
Guillermo MONTOYA, Nora JIMÉNEZ
doaj  

Permeable Hydrogel Encapsulated Osteosarcoma‐on‐a‐Chip for High‐Throughput Multi‐Drugs Screening

Smart Medicine
Pharmacological chemotherapy remains a cornerstone in treating osteosarcoma (OS), where the application of drug combinations not only enhances therapeutic efficacy but also mitigates adverse side effects. However, the absence of an efficient and reliable
Haiwen Su, Yuanhai Chen, Zhiyan Xuan, Haoyu Ren, Peihua Lu, Miaoqing Zhao, Huan Wang   +6 more
doaj   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Artificial Cilia for 360° Direction‐Sensitive Acoustic Sensing Through Additive Micromanufacturing

Advanced Electronic Materials
Directional acoustic sensing can be used for localization and detection, has a wide range of applications in various fields, including rescue robotics, drone positioning, and underwater navigation.
Yikang Li, Dazhi Wang, Yiwen Feng, Chang Liu, Xu Chen, Zefei Li, Xiangji Chen, Ran Zhang, Xiaopeng Zhang, Shiwen Liang, Liujia Suo, Weiwei Li, Guo Liu, Jifei Liu, Tiesheng Wang   +14 more
doaj   +1 more source

Chromatographic, Spectrometric and NMR Characterization of a New Set of Glucuronic Acid Esters Synthesized by Lipase [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2007
An enzymatic synthesis was developed on a new set of D-glucuronic acid esters and particularly the tetradecyl-D-glucopyranosiduronate also named tetradecyl D-glucuronate.
Michel Marlier, Michel Paquot, Patrick Rollin, Florence Chéry, Jacqueline Destain, Pascal Gerbaux, Georges Lognay, Christophe Blecker, Benoît Moreau   +8 more
doaj  

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

electrospray ionisation mass spectrometry (ESMS) ()

, 2023
dataset for electrospray ionisation mass spectrometry (ESMS) HRMS (ESI+, [M+H]+, C39H33AuClNP) calcd.: 778.1699; found: 778 ...
Zippel, Christoph, Knoll, Daniel
core   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Analysis of cell membrane aminophospholipids as isotope-tagged derivatives

Journal of Lipid Research, 2005
Glycerophosphoethanolamine (GPEtn) and glycerophosphoserine (GPSer) lipids were reacted with a multiplexed set of differentially isotopically enriched N-methylpiperazine acetic acid N-hydroxysuccinimide ester reagents, which place isobaric mass labels at
Karin A. Zemski Berry, Robert C. Murphy
doaj   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source