Results 141 to 150 of about 119,736 (261)

Ultrasmall Au10–12 Nanoclusters: A Novel Platform for 223Ra‐Targeted Tumor α‐Therapy

Exploration, EarlyView.
Encapsulating 223Ra in Au10‐12 nanoclusters and functionalizing them with RGD peptides enables targeted α‐therapy and immune microenvironment remodeling in non‐osseous tumors like triple‐negative breast cancer. This study establishes a foundational framework for novel 223Ra‐labeled α‐radiopharmaceuticals and shows strong potential for clinical ...
Yifei Jiang, Huizhen Yang, Guoping Jia, Wangxi Hai, Rongyi Huang, Peng Wang, Min Zhang, Danni Li, Yizhou Chen, Xiao Li, Biao Li, Chunfu Zhang   +11 more
wiley   +1 more source

Ionization efficiency prediction of electrospray ionization mass spectrometry analytes based on molecular fingerprints and cumulative neutral losses. [PDF]

J Cheminform
Nikolopoulos A, van Herwerden D, Turkina V, Kruve A, Baerenfaenger M, Samanipour S.   +5 more
europepmc   +1 more source

Simultaneous Quantification of Phenolic Compounds and Capsaicinoids in Chili Peppers Using Ultra‐High Performance Liquid Chromatography‐Tandem Mass Spectrometry

Food Safety and Health, EarlyView.
A UHPLC‐MS/MS method was developed to simultaneously quantify four capsaicinoids and 19 phenolic compounds, the key bioactive constituents in chili peppers. It exhibits high sensitivity, low matrix effects, excellent accuracy, and precision, enabling reliable detection in chili samples.
Shaoyun Wu, Xue Feng, Haixiao Ma, Yinfeng Zhao, Zhenying Sun, Meiling Zhang, Zehua Ke, Jing Qiu, Yongzhong Qian, Guiqiao Liu, Rui Weng   +10 more
wiley   +1 more source

Active Humidity Control Chamber for Desorption Electrospray Ionization-Mass Spectrometry Imaging Applications. [PDF]

J Am Soc Mass Spectrom
Shepard HS, Gottschalk RLG, May JC, McLean JA.   +3 more
europepmc   +1 more source

High‐Resolution Ion Mobility Approach for Rapid Determination of Multiple Human Milk Oligosaccharide Isomer Ratios

Helvetica Chimica Acta, EarlyView.
ABSTRACT This study presents a high‐throughput ion mobility approach that integrates flow injection analysis (FIA) with multiple stitched high‐resolution ion mobility ranges to enable comprehensive analysis of human milk oligosaccharide (HMO) isomer mixtures in a single acquisition.
Wenqing Xu, Estelle Rathahao‐Paris, Blanche Guillon, François Fenaille, Karine Adel‐Patient, Sandra Alves   +5 more
wiley   +1 more source

High-Throughput Drug Derivatization and Bioassay by Desorption Electrospray Ionization Mass Spectrometry. [PDF]

Chempluschem
Ghosh J, Morato NM, Feng Y, Cooks RG.
europepmc   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source

Antibody-Drug Conjugate Stability Probed by Variable-Temperature Electrospray Ionization Mass Spectrometry. [PDF]

J Am Soc Mass Spectrom
Fiala J, Schuster D, Heck AJR.
europepmc   +1 more source

Functionally complementary bacterial inoculant coordinates arbuscular mycorrhizal fungi to improve Angelica sinensis root yield and quality

iMetaOmics, EarlyView.
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang, Yun Wang, Jiecai Zhao, Gaofeng Chen, Andéole Niyongabo Turatsinze, Liang Yue, Yuan Tian, Xiaofan Xie, Ailing Ye, Meilan Zhang, Lingling Wu, Zengxiang Guo, Yubao Zhang, Ruoyu Wang   +13 more
wiley   +1 more source

Analysis of the dynamic metabolic changes during the ripening of wolfberry (<i>Lycium barbarum</i> L.) fruits by theta-nano-extractive electrospray ionization mass spectrometry. [PDF]

Food Chem X
Liu Y, Yu L, Yan S, Fang X, Zhu T, Chen H, Wu D.   +6 more
europepmc   +1 more source