Bead-Ejection Scenario in Electrospray Ionization of Multidomain Nucleic Acids. [PDF]
Ghosh D, Rosu F, Gabelica V.
europepmc +1 more source
A Drug‐Gated, Modular STAb‐T Immunotherapy With External Control
Engineered STAb‐TON cells act as programmable living factories that continuously secrete inactive antibody modules, which assemble extracellularly into a functional T cell engager only upon small‐molecule administration. This externally controlled platform enables reversible, on‐demand regulation of antitumor immunity, establishing a new paradigm for ...
Susana Luengo‐Arias +23 more
wiley +1 more source
Wooden-Tip Electrospray Ionization Mass Spectrometry Combined With Machine Learning for Differentiating Thyroid Tumours. [PDF]
Liu DS +10 more
europepmc +1 more source
Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen +6 more
wiley +1 more source
High-throughput chiral analysis using automated desorption electrospray ionization mass spectrometry. [PDF]
Li J +9 more
europepmc +1 more source
TH17–Associated Polyamine Metabolism‐Guided Nanozyme Promotes Alveolar Bone Repair in Periodontitis
A pronounced TH17‐skewed immune response is identified in experimental periodontitis, and enrichment of the polyamine pathway is observed during TH17 differentiation, suggesting its potential as an immunometabolic target. Inspired by these findings, DFMO@Ui‐Mn is developed as a therapeutic platform combining cascade ROS scavenging with immunometabolic ...
Cheng Zhu +12 more
wiley +1 more source
Regarding Emitter Positioning for Nanoflow Electrospray Ionization with a High-Capacity Inlet Capillary. [PDF]
Lancaster NM +3 more
europepmc +1 more source
A liquid‐phase ion trap (LPIT) coupled with ESI‐MS enables rapid, high‐fidelity de novo sequencing of long oligonucleotides in ∼30 min. By applying an electric field to dissociate metal adducts in solution, LPIT delivers clean spectra, superior mass accuracy, and full sequence coverage, surpassing MALDI‐TOF and LC‐MS.
Song Lu +5 more
wiley +1 more source
Advanced methods in fourier transform ion cyclotron resonance mass spectrometry [PDF]
Mass spectrometry (MS) is a powerful analytical technique used to characterize various compounds by measuring the mass-to-charge ratio (m/z). Among different types of mass analyzers, Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR ...
Qi, Yulin
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