Results 141 to 150 of about 682,349 (297)

Wooden-Tip Electrospray Ionization Mass Spectrometry Combined With Machine Learning for Differentiating Thyroid Tumours. [PDF]

Anal Sci Adv
Liu DS, Liu L, Wang B, Zhang J, Lin HG, Huang XX, Deng KJ, Zhou YT, Pan Y, Hu B, Huang XY.   +10 more
europepmc   +1 more source

Lipid and metabolite profiles of human brain tumors by desorption electrospray ionization-MS

Proceedings of the National Academy of Sciences of the United States of America, 2016
A. Jarmusch, V. Pirro, Zane Baird, E. Hattab, A. Cohen-Gadol, R. Cooks   +5 more
semanticscholar   +1 more source

Untangling Inositol (Pyro)Phosphate Biology Through Emerging Technologies

Advanced Science, EarlyView.
Inositol (pyro)phosphates represent a vital class of intracellular messengers that govern multiple biological processes. The last decade has experienced a surge of interest in the functions of this class of signaling molecules, primarily due to the introduction of several innovative analytical technologies.
Adolfo Saiardi, Mengsi Lu, Yue Zhang, Anuj Shukla, An‐Li Andrea Ko, Henning J. Jessen   +5 more
wiley   +1 more source

High-throughput chiral analysis using automated desorption electrospray ionization mass spectrometry. [PDF]

Chem Commun (Camb)
Li J, Morato NM, Hao B, Chen A, Jouffroy L, Kim H, Shi Z, Goossens K, Strambeanu II, Cooks RG.   +9 more
europepmc   +1 more source

The Critical Role of Fractionated Urine Glycosaminoglycans in the Evaluation of Mucopolysaccharidosis Type II in Four Unrelated Families

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Since 2015, Ann and Robert H. Lurie Children's Hospital has performed diagnostic testing for infants who screen positive for mucopolysaccharidosis type II (MPS II) on the Illinois newborn screen. Preliminary diagnostic testing includes measurement of plasma iduronate‐2‐sulfatase enzyme activity and urinary glycosaminoglycan analysis, followed ...
Carly A. Rasmussen, Monika Izdebski, Allison Paltzer, Rachel Hickey, Laura Pollard, Joshua Baker   +5 more
wiley   +1 more source

Protonation‐Gated Orthogonal Control of Highly Efficient Molecular Motors With Broad Visible‐Light Responsiveness

Angewandte Chemie, EarlyView.
Reversible protonation gates coumarin‐based overcrowded‐alkene molecular motors by dynamically reshaping their conjugation topology. This strategy enables efficient, near‐quantitative unidirectional photoisomerization from blue–green to red‐shifted visible light up to 600 nm, while preserving motor function and allowing orthogonal light, heat, and acid/
Jinghao Wang, Alexander Ryabchun, Ben L. Feringa   +2 more
wiley   +2 more sources

Regarding Emitter Positioning for Nanoflow Electrospray Ionization with a High-Capacity Inlet Capillary. [PDF]

J Am Soc Mass Spectrom
Lancaster NM, Quarmby ST, Overmyer KA, Coon JJ.   +3 more
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization

Angewandte Chemie, EarlyView.
The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu, Zeliang Zhang, Benedikt Seligmann, Van Hung Bui, Tuan‐Anh Minh Nguyen, Thu‐Thuy T. Dang, Jakob Franke   +6 more
wiley   +2 more sources

Dynamic Additive Scanning for Precise Control in Electrospray Ionization Mass Spectrometry. [PDF]

ACS Meas Sci Au
Wu IT, Elpa DP, Chien HN, Urban PL.
europepmc   +1 more source