Results 1 to 10 of about 16,991 (224)

Transmission mode desorption electrospray ionization [PDF]

Journal of the American Society for Mass Spectrometry, 2008
A new mode of operation for desorption electrospray ionization (DESI) analysis of liquids or solid residues from evaporated solvents is presented. Unlike traditional DESI, the electrospray is not deflected off of a surface but instead is transmitted through a sampling mesh at a 0 degrees angle between the electrospray tip, sample mesh, and capillary ...
Jennifer S Brodbelt
exaly   +4 more sources

Salt tolerance of desorption electrospray ionization (DESI) [PDF]

Journal of the American Society for Mass Spectrometry, 2007
The salt tolerance of desorption electrospray ionization (DESI) was systematically investigated by examining three different drug mixtures in the presence of 0, 0.2, 2, 5, 10, and 20% NaCl:KCl (1:1) from different surfaces. At physiological salt concentrations, the individual drugs in each mixture were observed in each experiment.
Ayanna U Jackson, R Graham Cooks, Gary J Van Berkel   +2 more
exaly   +4 more sources

Comparison of Mass Spectrometry Imaging by Desorption Electrospray Ionization (DESI) and Desorption Electro-Flow Focusing Ionization (DEFFI) [PDF]

Metabolites
Background: Among atmospheric-pressure mass spectrometry imaging (MSI) methods, desorption electrospray ionization (DESI) and desorption electro-flow focusing ionization (DEFFI) represent cost-effective, high-throughput approaches that utilize ...
Yunshuo Tian, Ruolun Wei, Yifan Meng, Richard N. Zare   +3 more
doaj   +2 more sources

Toward Depth-Resolved Analysis of Plant Metabolites by Nanospray Desorption Electrospray Ionization Mass Spectrometry [PDF]

Molecules, 2022
Nanospray desorption electrospray ionization (nano-DESI) is one of the ambient desorption ionization methods for mass spectrometry (MS), and it utilizes a steady-state liquid junction formed between two microcapillaries to directly extract analytes from ...
Sangwon Cha, Gyouwoong Jun, Yougyeong Park, Sung Jun An, Donghoon Lee   +4 more
doaj   +2 more sources

High-throughput analysis of tissue microarrays using automated desorption electrospray ionization mass spectrometry [PDF]

Scientific Reports, 2022
Tissue microarrays (TMAs) are commonly used for the rapid analysis of large numbers of tissue samples, often in morphological assessments but increasingly in spectroscopic analysis, where specific molecular markers are targeted via immunostaining.
Nicolás M. Morato, Hannah Marie Brown, Diogo Garcia, Erik H. Middlebrooks, Mark Jentoft, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, R. Graham Cooks   +7 more
doaj   +2 more sources

Desorption Electrospray Ionization Mass Spectrometry Imaging Illustrates the Quality Characters of Isatidis Radix [PDF]

Frontiers in Plant Science, 2022
For a long history, herbal medicines have made significant contributions to human health all around the world. However, the exploration of an effective approach to illustrate their inner quality remains a challenge.
Li-Xing Nie, Li-Xing Nie, Lie-Yan Huang, Xin-Ping Wang, Lin-Feng Lv, Xue-Xin Yang, Xiao-Fei Jia, Shuai Kang, Ling-Wen Yao, Zhong Dai, Shuang-Cheng Ma, Shuang-Cheng Ma   +11 more
doaj   +2 more sources

Targeted Desorption Electrospray Ionization Mass Spectrometry Imaging for Drug Distribution, Toxicity, and Tissue Classification Studies [PDF]

Metabolites, 2023
With increased use of mass spectrometry imaging (MSI) in support of pharmaceutical research and development, there are opportunities to develop analytical pipelines that incorporate exploratory high-performance analysis with higher capacity and faster ...
Andreas Dannhorn, Maria Luisa Doria, James McKenzie, Paolo Inglese, John G. Swales, Gregory Hamm, Nicole Strittmatter, Gareth Maglennon, Sadaf Ghaem-Maghami, Richard J. A. Goodwin, Zoltan Takats   +10 more
doaj   +2 more sources

Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions [PDF]

BMC Bioinformatics, 2022
Background Mass spectrometry imaging (MSI) data often consist of tens of thousands of mass spectra collected from a sample surface. During the time necessary to perform a single acquisition, it is likely that uncontrollable factors alter the validity of ...
Paolo Inglese, Helen Xuexia Huang, Vincen Wu, Matthew R. Lewis, Zoltan Takats   +4 more
doaj   +2 more sources

Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry [PDF]

Scientific Reports
Desorption electrospray ionization (DESI) tandem mass spectrometry (MS) is used to assess mutation status of isocitrate dehydrogenase (IDH) in human gliomas.
Mahdiyeh Shahi, Steven Pringle, Michael Morris, Diogo Moniz Garcia, Alfredo Quiñones-Hinojosa, R. Graham Cooks   +5 more
doaj   +2 more sources

Desorption Electrospray Ionization Mass Spectrometry: 20 Years. [PDF]

Acc Chem Res, 2023
Morato NM, Cooks RG.
europepmc   +3 more sources